Deanna L. Kroetz, PhD, BS Pharm
Dean
The Kroetz laboratory studies the molecular basis of interindividual variability in chemotherapy-induced peripheral neuropathy (CIPN). Genome-wide genotyping and exome sequencing are used to identify genetic biomarkers of peripheral neurotoxicity. Novel genes and pathways are functionally interrogated in human iPSC-derived sensory neurons to define the molecular basis for genetic association findings and therapeutic strategies for reversal or prevention are investigated.