Robert Curley, PhD
Title
Faculty Emeritus
Email Address
Phone Number
Education
- 1984, Please enter degree name, University of Wisconsin, Biochemistry
- 1982, PhD, West Virginia University, Pharmaceutical Sciences
- 1978, BS, University of Connecticut, Pharmacy
Honors
- AAPS Fellow, 2009
- Pfeiffer Memorial Fellowship, American Foundation for Pharmaceutical Education, 1993 - 1994
- National Research Service Fellowship, National Cancer Institute, 1982 - 1984
- Abe Plough Citation Fellow, American Foundation for Pharmaceutical Education, 1981 - 1982
- American Foundation for Pharmaceutical Education Fellowships, 1979 - 1981
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Patents
- C-Linked Glucuronide of 4-Hydroxybenzylretinone, Analogs Thereof, and Method of Using the Same to Inhibit Neoplastic Cell Growth (2011, May). US 2011/0212906 A1.
- 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8- tetramethyl-2-naphthalenyl)-1-propenyl]benzoic Acid Analogs and Method of Manufacture and Use Thereof (2009, July). U.S. Patent No. 7,968,602.
- C-Linked Glucuronide of 4-Hydroxybenzylretinone, Analogs Thereof, and Method of Using the Same to Inhibit Neoplastic Cell Growth (2009, January). U.S. Patent No. 8,026,220.
- 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8- tetramethyl-2-naphthalenyl)-1-propenyl]benzoic Acid Analogs and Method of Manufacture and Use Thereof (2005, June). U.S. Patent No. 7,585,894.
- C-Linked Glucuronide of 4-Hydroxybenzylretinone, Analogs Thereof, and Method of Using the Same to Inhibit Neoplastic Cell Growth (2005, May). U.S. Patent No. 7,528,114.
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Publications
- Eroglu, A.; Hruszkewycz, D.P.; dela Sena, C.; Narayanasamy, S.; Riedl, K.M.; Kopec, R.E.; Schwartz, S. J.; Curley, Jr., R.W.; Harrison, E.H. Naturally Occurring Eccentric Cleavage Products of Provitamin A beta-Carotene Function as Antagonists of Retinoic Acid Receptors J. Biol. Chem.. 2012 May; 287(19):15886-15895.
- Fleshman, M.K.; Lester, G.E.; Riedl, K.M.; Kopec, R.E.; Narayanasamy, S.; Curley, R.W., Jr.; Schwartz, S.J.; Harrison, E.H. Carotene and Novel Apocarotenoid Concentrations in Orange-Fleshed Cucumis melo Melons: Determinations of beta-Carotene Bioaccessibility and Bioavailability J. Agric. Food Chem.. 2011 Jan; 59 4448-4454.
- Shmarakov, I.; Fleshman, M.K.; D'Ambrosio, D.; Piantedosi, R.; Riedl, K.M.; Schwartz, S.J.; Curley, R.W., Jr.; von Lintig, J.; Rubin, L.P.; Harrison, E.H.; Blaner, W.S. Hepatic Stellate Cells are an Important Cellular Site for beta-Carotene Conversion to Retinoid Arch. Biochem. Biophys.. 2010 Jan; 504 3-10.
- Eroglu, A.; Hruszkewycz, D.P.; Curley, R.W., Jr.; Harrison, E.H. The Eccentric Cleavage Product of beta-Carotene, beta-apo-13-Carotenone, Functions as an Antagonist of RXRalpha Arch. Biochem. Biophys.. 2010 Jan; 504 11-16.
- Kopec, R.E.; Riedl, K.M.; Harrison, E.H.; Curley, R. W., Jr.; Hruszkewycz, D.P.; Clinton, S.K.; Schwartz, S.J. Identification and Quantitation of Apo-Lycopenals in Fruits, Vegetables, and Human Plasma J. Agric. Food Chem.. 2010 Jan; 58 3290-3296.
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