November 20, 2019
Mark Mitton-Fry, PhD, an assistant professor in The Ohio State University College of Pharmacy’s Division of Medicinal Chemistry and Pharmacognosy, received a Dr. Ralph and Marian Falk Medical Research Trust Transformational Award, marking the first time anyone from Ohio State has received this prestigious honor.
The Transformational Award Program provides $1 million for a two-year funding cycle and provides a bridge to the technology transfer process for moving an exciting healthcare innovation to the next step in commercial development.
According to its website, in order to receive the Transformational Award, applicants must first receive the Dr. Ralph and Marian Falk Medical Research Catalyst Award, a program to support high-risk, high-reward projects that address critical scientific and therapeutic roadblocks within the program’s principal areas of focus. Catalyst awardees must successfully attain the proposed milestones and benchmarks of the Catalyst Award, thus demonstrating its successful execution within the proposed budget and projected timeframe in order to be eligible to apply for the Transformational Award.
Dr. Mitton-Fry received the Catalyst Award in 2017 for his project, “Novel Therapies for MRSA and Innovative Methods for Tackling Bacterial Resistance.”
Dr. Mitton-Fry’s project, “Combating Antibiotic Resistance with Novel Bacterial Topoisomerase Inhibitors,” focuses on the design, synthesis and evaluation of novel bacterial topoisomerase inhibitors to treat infections caused by multidrug-resistant bacteria. His research team spans microbiology (Dr. Daniel Wozniak’s Lab), pharmacology (Dr. Jack Yalowich’s Lab), structural biology (Dr. Craig McElroy’s Lab), computational chemistry (Dr. Steffen Lindert’s Lab) and medicinal chemistry (Dr. Mitton-Fry’s lab).
Hired in 2016 as part of The Ohio State University Discovery Themes Initiative, Dr. Mitton-Fry was named co-director of the Prevention, Detection and Therapies Thematic Program for the Infectious Diseases Institute, a focus area of Discovery Themes.
“I am thrilled to be working with a multidisciplinary team to discover and advance new therapies in this area of high medical need,” Dr. Mitton-Fry said. “We are extremely grateful to the Dr. Ralph and Marian Falk Medical Research Trust for this Transformational Award as well as for the earlier Catalyst Award.”
About the Dr. Ralph and Marian Falk Medical Research Trust:
The Dr. Ralph and Marian Falk Medical Research Trust was created by Marian Falk in 1979 to support biomedical research. Mrs. Falk sought to fund “medical research to improve treatments of the past and eventually find cures for diseases for which no definite cure is known.” U.S. Trust, Bank of America, N.A., serves as Trustee for the Falk Medical Research Trust.