April 2, 2018
The Ohio State University College of Pharmacy held its 13th annual Research Day on Thursday, March 29, 2018, at the Drake Union to celebrate innovative research in the college.
Research Day provides faculty, staff and students the opportunity to present their research projects and findings and network with other potential collaborators. A poster competition takes place throughout the day where students have the opportunity to win cash prizes for their research projects.
After the poster presentation, Lang Li, PhD, Chair of the Department of Biomedical Informatics at The Ohio State University College of Medicine gave the keynote address titled, "Translational Pharmacoinformatics Approaches in the Drug Interaction Research".
Li developed an international reputation for his use of biomedical informatics and systems pharmacology to evaluate drug efficacies and adverse drug events. He and his team have successfully discovered and validated epidemiological and pharmacological data for drug interactions by using various large-scale biomedical data sources. His translational research has been funded by awards from the National Institutes of Health and the National Sciences Foundation. He is an author of over 175 manuscripts, and an investigator, co-investigator or mentor on 12 research awards totaling in more than $2 million a year in funding.
After Li’s presentation, Dr. Cynthia Carnes, senior associate dean for research and graduate education, presented the awards to the top-scored presenters.
“Research Day is a great way to see the breadth and depth of work happening across the college. Participants receive great value out of the interactions during the poster presentations. I received numerous comments on the high-quality of the presentations and the impressive work that is happening here,” said Dr. Carnes.
This year’s poster winners are listed by category below:
First place (tie) – Daniel Ankrah
Title: A DESCRIPTION OF THE NATIONAL CLAIMS DATABASE IN GHANA
Authors: Daniel Ankrah, Jesper Hallas, James Odei, Francis Asenso-Boadi, Macarius Donneyong
First place (tie) – Alix Leblanc
Title: TARGETING OATP1B2 TO AMELIORATE PACLITAXEL-INDUCED CHRONIC PERIPHERAL NEUROPATHY
Authors: Alix F. Leblanc, Jason A. Sprowl, Paola Alberti, Alessia Chiorazzi, William D. Arnold, Guido Cavaletti, Alex Sparreboom, and Shuiying Hu
Residents & Fellows:
First place – Nathan Seligson
Title: COMBINATION OF POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITION TO MELPHALAN CONDITIONING THERAPY PRIOR TO AUTOLOGOUS STEM HEMATOPOIETIC STEM CELL TRANSPLANT IN MULTIPLE MYELOMA
Authors: Nathan D. Seligson, Ernest Duah, Avinash K. Persaud, Zac C. VanGundy, Junan Li, Craig C. Hofmeister and Ming J. Poi
First place – Ezgi Karaesman
Title: DONOR SNPS IN IL1RL1, STRONGLY CORRELATED WITH SERUM SST2 CONCENTRATION, SIGNIFICANTLY ASSOCIATE WITH RISK OF ACUTE GVHD: IMPLICATIONS FOR DONOR SELECTION
Authors: Ezgi Karaesmen, Abbas Rizvi, Michael Sovic, Junke Wang, Sandeep Kumar Singh, Sachidanand Singh, Tao Wang, Michael Haagenson, Alex Dile, Leah Preus, Stephen R. Spellman, Stephanie J. Lee, Theresa E. Hahn, Sophie Paczesny, Lara Sucheston-Campbell
Second place – Avinash Persaud
Title: GENETIC VARIANTS OF DNA REPAIR GENES ASSOCIATED WITH DIFFERENTIAL RESPONSE TO HIGH-DOSE MELPHALAN AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN MULTIPLE MYELOMA PATIENTS
Authors: Avinash K. Persaud, Nathan D. Seligson, Jasmine A. Johnson, Junan Li, Douglas W. Sborov, Yu Kyoung Cho, Misty Lamprecht, Mitch A. Phelps, Craig C. Hofmeister, Ming J. Poi
Third place (tie) – Andrew Huntsman
Title: DEVELOPMENT OF THE PHYLLANTHUSMIN CLASS OF NATURAL PRODUCTS: SAR, MECHANISTIC PROBES, AND DRUG PROPERTY OPTIMIZATION
Authors: Andrew C. Huntsman, Alexandria Young, John L. Woodard, Hee-Byung Chai, Yulin Ren, Mitch A. Phelps, Alan D. Kinghorn, Joanna E. Burdette, James Fuchs
Third place (tie) – Tyler Wilson
Title: A SCAFFOLD HOPPING APPROACH FOR THE DEVELOPMENT OF A POTENT CLASS OF ALLOSTERIC HIV-1 INTEGRASE INHIBITORS
Authors: Tyler A. Wilson, Nicholas T. Cockroft, Janet Antwi, Pratibha C. Koneru, Matthew J. Kobe, Mamuka Kvaratskhelia, James R. Fuchs
PharmD & Undergraduate Students:
First place – Matthew Satariano
Title: STRUCTURAL REMODELING OF SODIUM-CALCIUM HANDLING NANODOMAINS IN CARDIOMYOPATHY
Authors: Matthew Satariano, Naveed Zaman, Justin Thomas, Rengasayee Veeraraghavan, Sandor Györke, Przemyslaw Radwański
The Center for Clinical and Translational Science (CCTS) Translational Science Award:
First place – Abbas Rizvi
Title: GENETIC ASSOCIATIONS WITH DAY +100 TRANSPLANT RELATED MORTALITY AFTER HLA-MATCHED UNRELATED DONOR BLOOD AND MARROW TRANSPLANTATION
Authors: Abbas Rizvi, Ezgi Karaesmen, Leah Preus, Philip L. McCarthy, Marcelo Pasquini, Sachidanand Singh, Sandeep Kumar Singh, Kenan Onel, Xiaochun Zhu, Stephen Spellman, Christopher Haiman, Daniel O. Stram, Loreall Pooler, Xie Sheng, Qianqian Zhu, Li Yan, Qian Liu, Qiang Hu, Song Liu, Alyssa I. Clay-Gilmour, Sebastiano Battaglia, David Tritchler, Theresa Hahn, Lara E Sucheston-Campbell