Rajgopal Govindarajan

Raj Govindarajan

Rajgopal Govindarajan, DVM, PhD

Professor
Pharmaceutics and Pharmacology
544 Riffe Building
govindarajan.21@osu.edu
(614) 247-8269

Professional Interests

Dr. Govindarajan’s laboratory is interested in understanding and overcoming drug resistance in pancreatic cancer. His training is in the areas of animal sciences, cancer biology and drug transport-based pharmacokinetics, and has extensively used cell and animal models to evaluate nucleoside and oligonucleotide therapies. He also developed several new insights into the pharmacology and cytotoxicity of nucleoside analog drugs. Current focuses in his laboratory are to understand the epigenetic alterations in pancreatic cancer and to evaluate novel epigenetic reversal agents for effective pancreatic cancer treatment. Understanding epigenetic regulation of pluripotent stem cell factors in microRNA biogenesis is also of interest.

Education

  • Postdoc - University of Washington, Seattle, WA
  • PhD - University of Nebraska Medical Center, Omaha, NE
  • MVSc - Indian Veterinary Research Institute, India
  • BVSc - Madras Veterinary College, TANUVAS, India

Honors

  • Research Scholar, 2015 - 2019
  • Guest Editor, 2015 - 2015
  • 2015 Reviewer, 2015 - 2015
  • Elected member, 2014 - 2017
  • 2013 Reviewer, 2013 - 2013
  • Deans Pharmacy Special Endowment Fund Award, 2013 - 2013
  • Cancer Research Award, 2012 - 2012
  • College of Pharmacy Meritorious Research Productivity Award, 2012 - 2012
  • Poster of Distinction, 2011 - 2011
  • Randy Ellison Cancer Research Award, 2011 - 2011
  • AAPS Exceptional Abstract & Podium Presentation Award, 2011 - 2011
  • Developmental Research Project Award, 2009 - 2010
  • Developmental Research Project Award, 2008 - 2009
  • Training Support Grant, 2007 - 2007
  • Exceptional Abstract & Podium Presentation Award, 2007 - 2007
  • Reichenbach Presidential Fellowship, 2004 - 2005
  • Norm and Bernice Harris Award for Outstanding Work in Cancer Research during Graduate Studies, 2003 - 2003
  • Graduate Fellowship, , 2002-2005, 2002 - 2005
  • Best Poster Award (II prize), 2002 - 2002
  • Senior Research Fellowship, 1999 - 2000
  • Junior Research Fellowship-Animal Biotechnology, 1997 - 1999

Journal Articles

  • Muruganandan S, Govindarajan R, Sinal CJ. Bone Marrow Adipose Tissue and Skeletal Health. Curr Osteoporos Rep. 2018 Aug;16(4):434-442.
  • Muruganandan S, Govindarajan R, McMullen NM, Sinal CJ. Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation. Stem Cells. 2017 03;35(3):711-724.
  • Mody HR, Hung SW, AlSaggar M, Griffin J, Govindarajan R. Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGFβ1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p. Mol Cancer Res. 2016 11;14(11):1124-1135.