Image

Website
Mark Mitton-Fry, PhD
Title
Assistant Professor
Unit / Department / Division
Medicinal Chemistry and Pharmacognosy
Address
Parks Hall
Email Address
Phone Number
Professional Interests
Professional Interests
Dr. Mitton-Fry’s research team is dedicated to inventing cures for multidrug-resistant bacterial infections. The lab uses the tools of synthetic medicinal chemistry to design and prepare innovative new molecules, and we collaborate broadly to evaluate their biological, pharmaceutical, and toxicological properties. Dr. Mitton-Fry also enjoys teaching students at all levels about antibacterial therapies.
Education
- 2002, PhD, University of Colorado Boulder
- 1996, BA, Carleton College
Journal Articles
- Li, L.; Okumu, A. A.; Nolan, S.; English, A.; Vibhute, S.; Lu, Y.; Hervert-Thomas, K.; Seffernick, J. T.; Azap, L.; Cole, S. L.; Shinabarger, D.; Koeth, L. M.; Lindert, S.; Yalowich, J. C.; Wozniak, D. J.; Mitton-Fry, M. J. 1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition. ACS Infect Dis, 2019, 5, 1115-1128.
- Li, L.; Okumu, A.; Dellos-Nolan, S.; Li, Z.; Karmahapatra, S.; English, A.; Yalowich, J. C.; Wozniak, D. J.; Mitton-Fry, M. J. Synthesis and Anti-staphylococcal activity of Novel Bacterial Topoisomerase Inhibitors with a 5-amino-1,3-dioxane Linker Moiety. Bioorg. Med. Chem. Lett. 2018, 28, 2477-2480.
- Mitton-Fry, M. J.Novel bacterial type II topoisomerase inhibitors In Medicinal Chemistry Reviews, Vol. 52, Bronson, J., Ed.; American Chemical Society, 2017, pp. 281-302.
- Li, L.; Okumu, A.; Dellos-Nolan, S.; Li, Z.; Karmahapatra, S.; English, A.; Yalowich, J. C.; Wozniak, D. J.; Mitton-Fry, M. J. Synthesis and Anti-staphylococcal activity of Novel Bacterial Topoisomerase Inhibitors with a 5-amino-1,3-dioxane Linker Moiety Bioorg. Med. Chem. Lett. 2018, 28, 2477-2480. DOI: 10.1016/j.bmcl.2018.06.003.
- Lall, M. S.; Tao, Y.; Arcari, J. T.; Boyles, D.; Brown, M. F.; Damon, D. B.; Lilley, S. C.; Mitton-Fry, M. J.; Starr, J. T.; Stewart, A. M.; Sun, J. Process Development for the Synthesis of Monocyclic -Lactam Core 17. Org. Process Res. Dev. 2018, 22, 212-218, DOI: 10.1021/acs.oprd.7b00359.
- View all journal articles