Macarius Donneyong, PhD, MPH

Associate Professor

Pharmacy Practice and Science

Research Areas: Division of Pharmacy Practice and Science, Medication Use & Outcomes

404 Riffe

Professional Interests

Dr. Donneyong's passion is to improve health equity with respect to the effectiveness, safety and adherence to prescribed medications through research. His research interests include drug-drug interactions - adverse drug events precipitated by exposure to poly-pharmacy among older adults, especially racial/ethnic minorities; and medication adherence - the role of social determinants of health and patient-provider relationships in racial/ethnic disparities in medication adherence.

Biography

Dr. Macarius Donneyong is an assistant professor with joint faculty appointments in the Division of Outcomes and Translational Sciences, College of Pharmacy (70%) and the Division of Health Services Management and Policy, College of Public Health. He is also a faculty affiliate of the Translational Data Analytics Institute (TDAI), Discovery Themes.

His career is characterized by sustained record of multidisciplinary scholarship in the field of pharmacoepidemiology. His research has focused on generating real-world evidence on the effectiveness, safety and acceptability (adherence) of prescribed medication use among patient populations that are under-represented in clinical trials of medications, especially among racial/ethnic minorities and older patient populations.

Dr. Donneyong's commitment to this field of research has resulted in the recognition of his research as exemplified by the extramural (NIH R01 and foundations) and intramural research awards that he has received to improve patient outcomes. His research has been published in top-tier peer-reviewed journals including, the British Medical Journal, Jama Internal Medicine, Circulation-Hear Failure, etc. He has also given multiple talks as an invited speaker at some of the top universities in the US.

His selfless services to professional scientific societies have been rewarded with leadership opportunities. For example, he is currently a board member of the American College of Epidemiology and also previously served as the chair of various committees in the society as well as the International Society of Pharmacoepidemiology (ISPE). Beyond services in professional societies, he is extremely active in shaping the field of pharmacoepidemiology through his services as an associate editor and as a reviewer of extramural research grants and manuscripts. He remains dedicated to teaching and training the next generation of researchers through both formal and informal pedagogical and mentorship activities.

Education

2013 - PhD, Epidemiology (minor Biostatistics), University of Louisville, Louisville, Kentucky
2009 - MPH, Missouri State University, Springfield, Missouri
2005 - BS, Nutrition and Food Science, University of Ghana, Legon, Ghana

Honors

2022: AIM-AHEAD (Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity) Leadership Fellowship
2020: ICPE (International Conference of Pharmacoepidemiology) All Access Spotlight Poster Winner in the category of Adherence for poster entitled, “The Role of The Patient-provider Relationship In Racial/ethnic Disparities In Nonadherence To Antihypertens
2016: First place (Connected Health Track), Grand HACK in Medicine, MIT Hacking Medicine
2015: Conference travel award, the American College of Epidemiology, Atlanta, GA
2013: The Graduate Dean’s citation award. University of Louisville 2009
2013: Outstanding dissertation (award nomination). School of Interdisciplinary and Graduate Studies, University of Louisville
2012: Dissertation completion award. University of Louisville. Louisville, Kentucky

Publications

Chang TJ, Bridges JFP, Bynum M, Jackson JW, Joseph JJ, Fischer MA, Lu B, Donneyong MM. Association Between Patient-Clinician Relationships and Adherence to Antihypertensive Medications Among Black Adults: An Observational Study Design. J Am Heart Assoc. 2021 Jul 20;10(14):e019943. doi: 10.1161/JAHA.120.019943. Epub 2021 Jul 9. PMID: 34238022.
Jin Q, Hart PA, Shi N, Joseph JJ, Donneyong M, Conwell DL, Clinton SK, Cruz- Monserrate Z, Brasky TM, Tinker LF, Liu S, Shadyab AH, Thomson CA, Qi L, Rohan T, Tabung FK. Dietary Patterns of Insulinemia, Inflammation and Glycemia, and Pancreatic Cancer Risk: Findings from the Women's Health Initiative. Cancer Epidemiol Biomarkers Prev. 2021 Jun;30(6):1229-1240. doi: 10.1158/1055-9965.EPI-20-1478. Epub 2021 Apr 7. PMID: 33827986; PMCID: PMC8172436.
Donneyong MM, Chang TJ, Pottegård A, Ankrah D, Asenso-Boadi F, Addo-Cobbiah V, Dsane-Selby L, Hallas J. Prevalence and quality of antihypertensive therapy among hypertension patients enrolled in the Ghana National Health Insurance Scheme. Pharmacoepidemiol Drug Saf. 2021 May 26. doi: 10.1002/pds.5298. Epub ahead of print. PMID: 34038608.
Jin Q, Shi N, Aroke D, Lee DH, Joseph JJ, Donneyong M, Conwell DL, Hart PA, Zhang X, Clinton SK, Cruz-Monserrate Z, Brasky TM, Jackson R, Tinker LF, Liu S, Phillips LS, Shadyab AH, Nassir R, Bao W, Tabung FK. Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women. Diabetes Care. 2021 Mar;44(3):707-714. doi: 10.2337/dc20-2216. Epub 2021 Jan 8. PMID: 33419931; PMCID: PMC7896263.
Salas M, Lopes LC, Godman B, Truter I, Hartzema AG, Wettermark B, Fadare J, Burger JR, Appenteng K, Donneyong M, Arias A, Ankrah D, Ogunleye OO, Lubbe M, Horne L, Bernet J, Gómez-Galicia DL, Del Carmen Garcia Estrada M, Oluka MN, Massele A, Alesso L, Herrera Comoglio R, da Costa Lima E, Vilaseca C, Bergman U. Challenges facing drug utilization research in the Latin American region. Pharmacoepidemiol Drug Saf. 2020 Nov;29(11):1353-1363. doi: 10.1002/pds.4989. Epub 2020 May 17. PMID: 32419226.
Donneyong MM, Chang TJ, Jackson JW, Langston MA, Juarez PD, Sealy-Jefferson S, Lu B, Im W, Valdez RB, Way BM, Colen C, Fischer MA, Salsberry P, Bridges JFP, Hood DB. Structural and Social Determinants of Health Factors Associated with County-Level Variation in Non-Adherence to Antihypertensive Medication Treatment. Int J Environ Res Public Health. 2020 Sep 14;17(18):6684. doi: 10.3390/ijerph17186684. PMID: 32937852; PMCID: PMC7557537.
Donneyong MM, Chang TJ, Roth JA, Guilds M, Ankrah D, Najafzadeh M, Xu WY, Chlebowski RT, Margolis K, Manson JE. The Women's Health Initiative Estrogen- alone Trial had differential disease and medical expenditure consequences across age groups. Menopause. 2020 Jun;27(6):632-639. doi: 10.1097/GME.0000000000001517. PMID: 32132440; PMCID: PMC7255959.
Juarez PD, Tabatabai M, Valdez RB, Hood DB, Im W, Mouton C, Colen C, Al- Hamdan MZ, Matthews-Juarez P, Lichtveld MY, Sarpong D, Ramesh A, Langston MA, Rogers GL, Phillips CA, Reichard JF, Donneyong MM, Blot W. The Effects of Social, Personal, and Behavioral Risk Factors and PM_2.5 on Cardio- Metabolic Disparities in a Cohort of Community Health Center Patients. Int J Environ Res Public Health. 2020 May 19;17(10):3561. doi: 10.3390/ijerph17103561. PMID: 32438697; PMCID: PMC7277630.
Vyas CM, Donneyong M, Mischoulon D, Chang G, Gibson H, Cook NR, Manson JE, Reynolds CF 3rd, Okereke OI. Association of Race and Ethnicity With Late-Life Depression Severity, Symptom Burden, and Care. JAMA Netw Open. 2020 Mar 2;3(3):e201606. doi: 10.1001/jamanetworkopen.2020.1606. PMID: 32215634; PMCID: PMC7325738.
Donneyong M, Reynolds C, Mischoulon D, Chang G, Luttmann-Gibson H, Bubes V, Guilds M, Manson J, Okereke O. Protocol for studying racial/ethnic disparities in depression care using joint information from participant surveys and administrative claims databases: an observational cohort study. BMJ Open. 2020 Jan 7;10(1):e033173. doi: 10.1136/bmjopen-2019-033173. PMID: 31915172; PMCID: PMC6955513.