Macarius Donneyong, PhD, MPH
Professional Interests
Research Areas:
Biography
Dr. Macarius Donneyong is an associate professor with joint faculty appointments in the Division of Outcomes and Translational Sciences, College of Pharmacy (70%) and the Division of Health Services Management and Policy, College of Public Health. He is also a faculty affiliate of the Translational Data Analytics Institute (TDAI), Discovery Themes.
His career is characterized by a sustained record of multidisciplinary scholarship in the field of pharmacoepidemiology. His research has focused on generating real-world evidence on the effectiveness, safety and acceptability (adherence) of prescribed medication use among patient populations that are under-represented in clinical trials of medications, especially among racial/ethnic minorities and older patient populations.
Dr. Donneyong's commitment to this field of research has resulted in the recognition of his research as exemplified by the extramural (NIH R01 and foundations) and intramural research awards that he has received to improve patient outcomes. His research has been published in top-tier peer-reviewed journals including, the British Medical Journal, Jama Internal Medicine, Circulation-Hear Failure, etc. He has also given multiple talks as an invited speaker at some of the top universities in the US.
His selfless services to professional scientific societies have been rewarded with leadership opportunities. For example, he is currently a board member of the American College of Epidemiology and also previously served as the chair of various committees in the society as well as the International Society of Pharmacoepidemiology (ISPE). Beyond services in professional societies, he is extremely active in shaping the field of pharmacoepidemiology through his services as an associate editor and as a reviewer of extramural research grants and manuscripts. He remains dedicated to teaching and training the next generation of researchers through both formal and informal pedagogical and mentorship activities.
Education
- 2013 - PhD, Epidemiology (minor Biostatistics), University of Louisville, Louisville, Kentucky
- 2009 - MPH, Missouri State University, Springfield, Missouri
- 2005 - BS, Nutrition and Food Science, University of Ghana, Legon, Ghana
Honors
- 2022: AIM-AHEAD (Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity) Leadership Fellowship
- 2020: ICPE (International Conference of Pharmacoepidemiology) All Access Spotlight Poster Winner in the category of Adherence for poster entitled, “The Role of The Patient-provider Relationship In Racial/ethnic Disparities In Nonadherence To Antihypertens
- 2016: First place (Connected Health Track), Grand HACK in Medicine, MIT Hacking Medicine
- 2015: Conference travel award, the American College of Epidemiology, Atlanta, GA
- 2013: The Graduate Dean’s citation award. University of Louisville 2009
- 2013: Outstanding dissertation (award nomination). School of Interdisciplinary and Graduate Studies, University of Louisville
- 2012: Dissertation completion award. University of Louisville. Louisville, Kentucky
Publications
- Agreement between Surveillance, Epidemiology, and End Results– and Medicare Claims–Derived Uterine Cancer Treatment Data, Cancer Epidemiology, Biomarkers & Prevention. 2026 Mar | journal-article. doi: 10.1158/1055-9965.EPI-25-1483.
- Disaggregating Health Differences and Disparities With Machine Learning and Observed-to-expected Ratios: Application to Major Lower Limb Amputation, Epidemiology. 2025 Nov | journal-article. doi: 10.1097/EDE.0000000000001892.
- Proton Pump Inhibitor Use and Incident Hypertension in Menopausal Women, Journal of the American Heart Association. 2025 Jul | journal-article. doi: 10.1161/JAHA.124.040009.
- Prevalence of potentially inappropriately prescribed medications among older adults receiving peritoneal dialysis, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2025 Apr | journal-article. doi: 10.1002/phar.70008.
- Medication adherence among patients with disability: A systematic review, Annals of Epidemiology. 2024 Sep | journal-article. doi: 10.1016/j.annepidem.2024.07.012.
- Patient satisfaction with the quality of care received is associated with adherence to antidepressant medications, PLOS ONE. 2024 Jan | journal-article. doi: 10.1371/journal.pone.0296062.
- Potentially Inappropriately Medication Prescriptions Among Medicare Patients Receiving Hemodialysis, American Journal of Kidney Diseases. 2024 Jan | journal-article. doi: 10.1053/j.ajkd.2023.11.012.
- Optimizing Medication Distribution in Automated Dispensing Cabinets: Dashboard Implementation and Evaluation, Journal of Pharmacy Practice. 2023 Dec | journal-article. doi: 10.1177/08971900221118159.
- A comprehensive assessment of statin discontinuation among patients who concurrently initiate statins and CYP3A4‐inhibitor drugs; a multistate transition model, British Journal of Clinical Pharmacology. 2023 Jul | journal-article. doi: 10.1111/bcp.15373.
- Examining the Drivers of Racial/Ethnic Disparities in Non-Adherence to Antihypertensive Medications and Mortality Due to Heart Disease and Stroke: A County-Level Analysis., International journal of environmental research and public health. 2021 Dec | journal-article. doi: 10.3390/ijerph182312702.
- Changing patterns in medication prescription for gestational diabetes during a time of guideline change in the USA: a cross-sectional study., BJOG : an international journal of obstetrics and gynaecology. 2021 Nov | journal-article. doi: 10.1111/1471-0528.16960.
- Prevalence and quality of antihypertensive therapy among hypertension patients enrolled in the Ghana National Health Insurance Scheme, Pharmacoepidemiology and Drug Safety. 2021 Nov | journal-article. doi: 10.1002/pds.5298.
- A multistate transition model for statin-induced myopathy and statin discontinuation., CPT: pharmacometrics & systems pharmacology. 2021 Sep | journal-article. doi: 10.1002/psp4.12691.
- Random control selection for conducting high-throughput adverse drug events screening using large-scale longitudinal health data., CPT: pharmacometrics & systems pharmacology. 2021 Aug | journal-article. doi: 10.1002/psp4.12673.
- Association of Cardiovascular Disease and Long-Term Exposure to Fine Particulate Matter (PM2.5) in the Southeastern United States, Atmosphere. 2021 Jul | journal-article. doi: 10.3390/atmos12080947.
- Association Between Patient‐Clinician Relationships and Adherence to Antihypertensive Medications Among Black Adults: An Observational Study Design, Journal of the American Heart Association. 2021 Jul | journal-article. doi: 10.1161/JAHA.120.019943.
- A comprehensive assessment of statin discontinuation among patients who concurrently initiate statins and CYP3A4-inhibitor drugs; a multistate transition model, . 2021 May | other. doi: 10.1101/2021.05.13.21252626.
- Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women., Diabetes care. 2021 Jan | journal-article. doi: 10.2337/dc20-2216.
- Structural and Social Determinants of Health Factors Associated with County-Level Variation in Non-Adherence to Antihypertensive Medication Treatment., International journal of environmental research and public health. 2020 Sep | journal-article. doi: 10.3390/ijerph17186684.
- The Women's Health Initiative Estrogen-alone Trial had differential disease and medical expenditure consequences across age groups., Menopause (New York, N.Y.). 2020 Jun | journal-article. doi: 10.1097/gme.0000000000001517.
- The Effects of Social, Personal, and Behavioral Risk Factors and PM2.5 on Cardio-Metabolic Disparities in a Cohort of Community Health Center Patients., International journal of environmental research and public health. 2020 May | journal-article. doi: 10.3390/ijerph17103561.
- Challenges facing drug utilization research in the Latin American region., Pharmacoepidemiology and drug safety. 2020 May | journal-article. doi: 10.1002/pds.4989.
- Association of Race and Ethnicity With Late-Life Depression Severity, Symptom Burden, and Care., JAMA network open. 2020 Mar | journal-article. doi: 10.1001/jamanetworkopen.2020.1606.
- Protocol for studying racial/ethnic disparities in depression care using joint information from participant surveys and administrative claims databases: an observational cohort study, BMJ Open. 2020 Jan | journal-article. doi: 10.1136/bmjopen-2019-033173.
- Cost-sharing payments for out-of-network care in commercially insured adults., The American journal of managed care. 2019 Dec | journal-article. .
- A review of the Ghana National Health Insurance Scheme claims database: possibilities and limits for drug utilization research., Basic & clinical pharmacology & toxicology. 2018 Oct | journal-article. doi: 10.1111/bcpt.13136.
- Social Media Impact of the Food and Drug Administration's Drug Safety Communication Messaging About Zolpidem: Mixed-Methods Analysis, JMIR Public Health and Surveillance. 2018 Jan | journal-article. doi: 10.2196/publichealth.7823.
- Trends and Patterns of Corticosteroid Use During Coronary Artery Bypass Grafting Surgery in the United States., Journal of cardiovascular pharmacology and therapeutics. 2017 Dec | journal-article. doi: 10.1177/1074248417743334.
- Variation in adherence to medications across the healthcare system in two comparative effectiveness research cohorts., Journal of comparative effectiveness research. 2017 Oct | journal-article. doi: 10.2217/cer-2016-0095.
- Time From Emergency Department Evaluation to Operation and Appendiceal Perforation., Pediatrics. 2017 May | journal-article. doi: 10.1542/peds.2016-0742.
- Changes in prescribing and healthcare resource utilization after FDA Drug Safety Communications involving zolpidem-containing medications., Pharmacoepidemiology and drug safety. 2017 Apr | journal-article. doi: 10.1002/pds.4215.
- Clinical Outcomes of Concomitant Use of Warfarin and Selective Serotonin Reuptake Inhibitors: A Multidatabase Observational Cohort Study., Journal of clinical psychopharmacology. 2017 Apr | journal-article. doi: 10.1097/jcp.0000000000000658.
- Impact of an Interaction Between Clopidogrel and Selective Serotonin Reuptake Inhibitors., The American journal of cardiology. 2016 Nov | journal-article. doi: 10.1016/j.amjcard.2016.10.052.
- Risk of mortality with concomitant use of tamoxifen and selective serotonin reuptake inhibitors: multi-database cohort study., BMJ (Clinical research ed.). 2016 Sep | journal-article. doi: 10.1136/bmj.i5014.
- Effect of Generic Competition on Atorvastatin Prescribing and Patients' Out-of-Pocket Spending., JAMA internal medicine. 2016 Sep | journal-article. doi: 10.1001/jamainternmed.2016.3384.
- A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women., Bone reports. 2016 Aug | journal-article. doi: 10.1016/j.bonr.2016.08.005.
- Is outdoor recreational activity an independent predictor of cardiovascular disease mortality - NHANES III?, Nutrition, metabolism, and cardiovascular diseases : NMCD. 2016 Mar | journal-article. doi: 10.1016/j.numecd.2016.02.008.
- Idiopathic Pulmonary Fibrosis in United States Automated Claims. Incidence, Prevalence, and Algorithm Validation., American journal of respiratory and critical care medicine. 2015 Nov | journal-article. doi: 10.1164/rccm.201504-0818oc.
- Preoperative Aspirin Use and Its Effect on Adverse Events in Patients Undergoing Cardiac Operations., The Annals of thoracic surgery. 2015 Apr | journal-article. doi: 10.1016/j.athoracsur.2015.02.032.
- Risk of heart failure among postmenopausal women: a secondary analysis of the randomized trial of vitamin D plus calcium of the women's health initiative., Circulation. Heart failure. 2014 Nov | journal-article. doi: 10.1161/circheartfailure.114.001738.
- Determination of the optimum number of cardiac cycles to differentiate intra-pulmonary shunt and patent foramen ovale by saline contrast two- and three-dimensional echocardiography., . 2014 Mar | journal-article. doi: 10.1111/echo.12360.
- The Association of Pretransplant HeartMate II Left Ventricular Assist Device Placement and Heart Transplantation Mortality., . 2014 Jan | journal-article. doi: 10.1097/MAT.0000000000000065.