Liva Rakotondraibe

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Harinantenaina Liva Rakotondraibe

Liva Rakotondraibe, PhD

Title
Assistant Professor
Unit / Department / Division
Medicinal Chemistry and Pharmacognosy
Address
434 Parks Hall
Email Address
Phone Number

Professional Interests

Professional Interests

New natural product sources (new and unidentified fungal and bacterial microorganisms, microbial endophytes, new endemic and medicinal plant species, etc.) contain many undiscovered potential bioactive secondary metabolites that can be used to combat world’s deadly diseases including cancer, malaria, viral infections, and chemoresistance. Their investigation must be prioritized in order to discover new pharmacophores for potential drug candidates. My lab focuses on (1) bioassay-guided isolation, structural elucidation and development of bioactive compounds from natural sources, (2) Drug discovery from Madagascan natural products and (3) drug discovery from ethnomedicine. One of our recent ongoing projects is on the development of insecticides that can be used to control mosquito vector of Zika virus from Madagascan endemic plants. 

Education

  • 2003, PhD, Hiroshima University, Pharmaceutical Sciences (Medicinal Natural Product Chemistry
  • 1998, DEA (Diplome d'Etude Approfondie), Equivalent to MS, Mention "Tres bien", University of Antananarivo, Organic Chemistry/ Natural Product Chemistry

Honors

  • JSPS-Bridge (Japanese Society for the Promotion of Science) Fellowship, 2017 - 2018
  • 2016 Deans List, 2016
  • NIG, 2015 - 2017
  • Internal Seed Grant, 2015 - 2016
  • Postdoctoral Fellowship from the Japanese Society for the Promotion of Science (JSPS), 2005 - 2007
  • Japanese Government (Mombukagakusho): Ministry of Education, Culture, Sports, Science and Technology (MEXT), 1999 - 2003

Journal Articles

  • Rakotondraibe, L.R.; Dai, Y.; Liu, Y. Novel Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms (2009–2017) Chemical and Pharmaceutical Bulletin. 2018 May; 66(5):469-482.
  • Karmahapatra, S.; Kientz, C.; Shetty, S.; Yalowich, J.C. et al. Capsicodendrin from Cinnamosma fragrans Exhibits Antiproliferative and Cytotoxic Activity in Human Leukemia Cells: Modulation by Glutathione. J Nat Prod. 2018 Mar; 81(3):625-629.
  • Wilson, T.A.; Tokarski, R.J.; Sullivan, P.; Demoret, R.M. et al. Total Synthesis of Scytonemide A Employing Weinreb AM Solid-Phase Resin. J Nat Prod. 2018 Mar; 81(3):534-542.
  • Inocente, E.A.; Shaya, M.; Acosta, N.; Rakotondraibe, L.H. et al. A natural agonist of mosquito TRPA1 from the medicinal plant Cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito Aedes aegypti. PLoS Negl Trop Dis. 2018 Feb; 12(2):e0006265.
  • Tan, C.Y.; Inagaki, M.; Chai, H.B.; Lambrechts, M.K. et al. Phytochemical and cytotoxic investigations of pinguisanoids from liverwort Porella cordaeana Phytochemistry Letters. 2017 Mar; 19 77-82.
  • He, D.; Slebodnick, C.; Rakotondraibe, L.H. Bioactive drimane sesquiterpenoids and aromatic glycosides from Cinnamosma fragrans Bioorganic and Medicinal Chemistry Letters. 2017 Jan; 27(8):1754-1759.
  • Kinghorn, A.D.; Carcache de Blanco, E.J.; Lucas, D.M.; Rakotondraibe, L.H. et al. Discovery of Anticancer Agents of Diverse Natural Origin Anticancer Res. 2016 Nov; 36(11):.
  • Rakotondraibe, L.H. Review of Problems in Organic Structure Determination. A Practical Approach to NMR Spectroscopy J. Nat. Prod.. 2016 Jun; 79 0000-0000.
  • Pan, C.C.; Shah, N.; Kumar, S.; Wheeler, S.E. et al. Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy oncotarget. 2016 May; 00 0000-0000.
  • Al-Jabban, S.M.R.; Zhang, X.; Chen, G.; Rakotondraibe, L.H. et al. Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect. Nat Prod Commun. 2016 Apr; 11(4):465-468.
  • Nagashima, F.; Tabuchi, Y.; Ito, T.; Harinantenaina, L. et al. Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants. Nat Prod Commun. 2016 Feb; 11(2):153-157.
  • Rakotondraibe, L.H.; Rasolomampianina, R.; Park, H.Y.; Li, J. et al. Antiproliferative and Antiplasmodial Compounds from Selected Streptomyces species Bioorganic Medicinal Chemistry Letters. 2015 Dec; 25 5646-5649.
  • Al-Jabban, S.M.R.; Zhang, X.; Chen, G.; Mekuria, A.E. et al. Synthesis and Anti-Proliferative Effects of Quercetin Derivatives Nat. Prod. Comm.,. 2015 Dec; 10 2113-2118.
  • Presley, C.C.; Rakotondraibe, L.H.; Brodie, P.J.; Callmander, M.W. et al. A Synthetic Butenolide Diterpene is now a Natural Product Isolated from Metaporana sericosepala, a Plant from the Madagascar Dry Forest. Nat Prod Commun.. 2015 Sep; 10 1505-1507.
  • Pan, L.; Muñoz Acuña, U.; Chai, H.; Park, H.Y. et al. New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis. Planta Mediva. 2015 Aug; 81 1133-1140.
  • Chen, Q.H.; Yu, K.; Zhang, X.; Chen, G. et al. A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: Design, synthesis, and anti-proliferative evaluation Bioorg. Med. Chem. Lett.. 2015 Aug; 25 4553-4556.
  • Liu, Y.; Young, K.; Rakotondraibe, L.H.; Brodie, P.J. et al. Antiproliferative Compounds from Cleistanthus boivinianus from the Madagascar Dry Forest J. Nat. Prod.. 2015 Jul; 78 1543-1547.
  • Addo, E.M.; Chai, H.B.; Hymete, A.; Yeshak, M.Y. et al. Antiproliferative Constituents of the Roots of Ethiopian Podocarpus falcatus and Structure Revision of 2α-Hydroxynagilactone F and Nagilactone I J Nat Prod.. 2015 Jul; 78 827-835.
  • Eaton, A.L.; Harinantenaina, L.; Brodie, P.J.; Goetz, M. et al. New antiproliferative trihydroxyalkylcyclohexenones from Pleiogynium timoriense J. Nat. Prod.. 2015 Jul; 78(11):1752-1755.
  • Liu, Y.; Rakotondraibe, L.H.; Brodie, P.J.; Wiley, J.D. et al. Antimalarial 5,6-Dihydro-α-pyrones from Cryptocarya rigidifolia: Related Bicyclic Tetrahydro-α-Pyrones Are Artifacts J. Nat. Prod. 2015 Jun; 78 1330-1338.
  • Liu, Y.; Cheng, E.; Rakotondraibe, L.H.; Brodie, P.J. et al. Antiproliferative Compounds from Ocotea macrocarpa from the Madagascar Dry Forest Tetrahedron Lett.. 2015 Jun; 56 3630-3632.
  • Sohrabi, R.; Huh, J.H.; Badieyan, S.; Rakotondraibe, L.H. et al. In planta variation of volatile biosynthesis: an alternative biosynthetic route to the formation of the pathogen-induced volatile homoterpene DMNT via triterpene degradation in Arabidopsis roots. Plant Cell. 2015 Mar; 27(3):874-890.
  • Rakotondraibe, L.H.; Graupner, P.R.; Xiong, Q.; Olson, M. et al. Neolignans and other metabolites from Ocotea cymosa from the Madagascar rain forest and their biological activities J. Nat. Prod.. 2015 Mar; 78(3):431-40.
  • Nomoto, Y.; Harinantenaina, L.; Sugimoto, S.; Matsunami, K. et al. 3,4-seco-24-homo-28-nor-Cycloartane and drimane-type sesquiterpenes and their lactams from the EtOAc-soluble fraction of a leaf extract of Cinnamosma fragrans and their biological activity. J Nat Med. 2014 Jul; 68(3):513-520.
  • Rasamison, V.E.; Rakotondraibe, L.H.; Slebodnick, C.; Brodie, P.J. et al. Nitrogen-Containing Dimeric nor-Multiflorane Triterpene from a Turraea sp. Organic Letters. 2014 Apr; 16 2626-2629.
  • Dai, Y.; Harinantenaina, L.; Bowman, J.D.; Da, F.I.O. et al. Isolation of antiplasmodial anthraquinones from Kniphofia ensifolia, and synthesis and structure-activity relationships of related compounds Bioorg. Med. Chem.. 2014 Jan; 22 269-276.
  • Liu, Y.; Harinantenaina, L.; Brodie, P.J.; Bowman, J.D. et al. Bioactive compounds from Stuhlmannia moavi from the Madagascar dry forest Bioorg. Med. Chem.. 2013 Dec; 21 7591-7594.
  • Nomoto, Y.; Harinantenaina, L.; Sugimoto, S.; Matsunami, K. et al. C-Glycosyl flavonoids and coloratane-type sesquiterpene glucosides from the water-soluble fraction of a leaf extract of a Malagasy endemic plant, Cinnamosma fragrans (Canellaceae). J Nat Med. 2013 Oct; 67(4):736-742.
  • Eaton, A.L.; Harinantenaina, L.; Brodie, P.J.; Cassera, M.B. et al. A new bioactive diterpene glycoside from Molinaea retusa from the Madagascar dry forest. Nat Prod Commun. 2013 Sep; 8(9):1201-1203.
  • Liu, Y.; Harinantenaina, L.; Brodie, P.J.; Slebodnick, C. et al. Structure elucidation of antiproliferative bisbenzylisoquinoline alkaloids from Anisocycla grandidieri from the Madagascar dry forest. Magnetic resonance in chemistry. 2013 Sep; 51(9):574-579.
  • Harinantenaina, L.; Brodie, P.J.; Maharavo, J.; Bakary, G. et al. Antiproliferative homoscalarane sesterterpenes from two Madagascan sponges Bioorg. Med. Chem.. 2013 Jun; 21 2912-2917.
  • Dai, Y.; Harinantenaina, L.; Brodie, P.J.; Goetz, M. et al. Antiproliferative Homoisoflavonoids and Bufatrienolides from Urginea depressa J. Nat Prod.. 2013 May; 76 865-872.
  • Kawakami, S.; Toyoda, H.; Harinantenaina, L.; Matsunami, K. et al. Eight New Diterpenoids and Two New Nor-Diterpenoids from the Stems of Croton cascarilloides Chem. Pharm. Bull.. 2013 Feb; 61 411-418.
  • Dai, Y.; Harinantenaina, L.; Brodie, P.J.; Birkinshaw, C. et al. Antiproliferative Triterpene Saponins from Nematostylis anthophylla from the Madagascar Dry Forest Chemistry and Biodiversity. 2013 Feb; 10 233-240.
  • Harinantenaina, L.; Bowman, J.; Brodie, P.; Slebodnick, C. et al. Antiproliferative and antiplasmodial dimeric phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest J. Nat. Prod.. 2013 Jan; 76 388-393.
  • Dai, Y.; Harinantenaina, L.; Brodie, P.J.; Callmander, M.W. et al. Isolation and Synthesis of Two Antiproliferative Calamenene-type Sesquiterpenoids from Sterculia capuronii from the Madagascar Rain Forest Bioorg. Med. Chem.. 2012 Oct; 20 6940-6944.
  • Harinantenaina, L.; Brodie, P.J.; Callmander, M.W.; Razafitsalama, L.J. et al. Two antiproliferative saponins of Tarenna grevei from the Madagascar dry forest Nat. Prod. Comm.. 2012 Jun; 7 705-708.
  • Iwamoto, Y.; Sugimoto, S.; Harinantenaina, L.; Matsunami, K. et al. Entadosides A-D, triterpene saponins and a glucoside of the sulphur-containing amide from the kernel nuts of Entada phaseoloides (L.) Merrill JOURNAL OF NATURAL MEDICINES. 2012 Apr; 66(2):321-328.
  • Asakawa, Y.; Ludwiczuka, A.; Harinantenaina, L.; Toyota, M. et al. Distribution of Drimane Sesquiterpenoids and Tocopherols in Liverworts, Ferns and Higher Plants: Polygonaceae, Canellaceae and Winteraceae Species Nat. Prod. Comm.. 2012 Mar; 7 685-692.
  • Dai, Y.; Harinantenaina, L.; Brodie, P.J.; Callmander, M.W. et al. Antiproliferative Acetogenins from a Uvaria sp. from the Madagascar Dry Forest J. Nat. Prod.. 2012 Mar; 75 479-483.
  • Macahig, R.A.; Harinantenaina, L.; Sugimoto, S.; Matsunami, K. et al. Glucosylated sesquiterpene alcohols from Fraxinus griffithii Nat. Prod. Comm.. 2012 Feb; 7 467-470.
  • Clark, V.C.; Harinantenaina, L.; Zeller, M.; Zeller, W. et al. An Endogenous Bile Acid and Dietary Sucrose from Skin Secretions of Alkaloid-Sequestering Poison Frogs J. Nat. Prod.. 2012 Jan; 75 473-478.
  • Pan, E.; Gorka, A.P.; Alumasa, J.N.; Slebodnick, C. et al. Antiplasmodial and Antiproliferative Pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. J. Nat. Prod.. 2011 Nov; 74 2174-2180.
  • Sumioka, H.; Harinantenaina, L.; Matsunami, K.; Otsuka, H. et al. Linderolides A–F, eudesmane-type sesquiterpene lactones and linderoline, a germacrane-type sesquiterpene from the roots of Lindera strychnifolia and their inhibitory activity on NO production in RAW 264.7 cells in vitro Phytochemistry. 2011 Oct; 72 2165-2171.
  • Harinantenaina, L.; Brodie, P.J.; Slebodnick, C.; Callmander, M.W. et al. Antiproliferative Compounds from Pongamiopsis pervilleana from the Madagascar Dry Forest JOURNAL OF NATURAL PRODUCTS. 2011 Sep; 73 1792-1795.
  • Harinantenaina, L.; Brodie, P.J.; Callmander, M.; Randrianaivo, R. et al. Astrotricoumarin, an antiproliferative 4'-hydroxy-2',3'-dihydroprenylated methylcoumarin from an Astrotrichilia sp.from the Madagascar dry forest Nat. Prod. Comm.. 2011 Sep; 6 1259-1262.
  • Pan, E.; Harinantenaina, L.; Brodie, P.J.; Callmander, M. et al. Cardenolides of Leptadenia madagascariensis from the Madagascar dry forest Bioorg. Med. Chemi.. 2011 Jan; 19 422-442.
  • Hou, Y.; Rakotondraibe, L.H. New and Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms. Curr. Med. Chem.. 2010 Dec; 17 .
  • Yangpeng, Hou, Liva Harinantenaina New and Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms. Current Medicinal Chemistry Curr. Med. Chem.. 2010 Dec; 17 1191-1219.
  • Pan, E.; Harinantenaina, L.; Brodie, P.J.; Miller, J.S. et al. Four Diphenylpropanes and a Cycloheptadibenzofuran from Bussea sakalava from the Madagascar Dry Forest J. Nat. Prod.. 2010 Nov; 37 1792-1795.
  • Hou, Y.; Harinantenaina, L. New and Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms CURRENT MEDICINAL CHEMISTRY. 2010 Apr; 17(12):1191-1219.
  • Macahig, R.A.; Harinantenaina, L.; Matsunami, K.; Otsuka, H. et al. Secoiridoid and iridoid glucosides from the leaves of Fraxinus griffithii J. Nat. Med. 2010 Jan; 64 1-8.
  • Asakawa, Y.; Ludwiczuk, A.; Nagashima, F.; Toyota, M. et al. Bryophytes: Bio- and chemical diversity, Bioactivity and Chemosystematics Heterocycles. 2009 Dec; 77 99-150.
  • Harinantenaina, L.; Matsunami, K.; Otsuka, H. Chemical constituents of Pteris cretica Linn. (Pteridaceae) BIOCHEMICAL SYSTEMATICS AND ECOLOGY. 2009 Apr; 37(2):133-137.
  • Harinantenaina, L.; Matsunami, K.; Otsuka, H. Chemical constituents of Pteris cretica Biochem. Syst. and Ecol. 2009 Feb; 37 133-137.
  • Kawakami, S.; Harinantenaina, L.; Matsunami, K.; Otsuka, H. et al. Macaflavanones A-G, Prenylated Flavanones from the Leaves of Macaranga tanarius J. Nat. Prod.. 2008 Nov; 71 1872-1876.
  • Yoshinori, A.; Masao, T.; Toshihiro, H.; Motoo, T. et al. MARCHANTIOPHYTA (LIVERWORTS): RICH SOURCES OF MACROCYCLIC BIS(BIBENZYLS) HETEROCYCLES. 2008 Sep; 76(1):99-127.
  • Harinantenaina, L.; Matsunami, K.; Otsuka, H. Chemical and biologically active constituents of Pteris multifida J. Nat. Med.. 2008 Apr; 62 452-455.
  • Harinantenaina, L.; Matsunami, K.; Otsuka, H.; Kawahata, M. et al. Secondary Metabolites of Cinnamosma madagascariensis and Their alpha-Glucosidase Inhibitory Properties JOURNAL OF NATURAL PRODUCTS. 2008 Apr; 71 123-126.
  • Harinantenaina, L.; Asakawa, Y. Chemical constituents of malagasy liverworts. 6. A myltaylane caffeate with nitric oxide inhibitory activity from Bazzania nitida JOURNAL OF NATURAL PRODUCTS. 2007 May; 70(5):856-858.
  • Harinantenaina, L.; Asakawa, Y. Chemical Constituents of Malagasy Liverworts, Part VI: A myltaylane caffeate from Bazzania nitidawith nitric oxide inhibitory activity J. Nat. Prod.. 2007 May; 70 856-858.
  • Harinantenaina, L.; Asakawa, Y.; De Clercq, E. Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa. J Nat Prod. 2007 Feb; 70(2):277-282.
  • Harinantenaina, L.; Asakawa, Y.; De Clercq, E. Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with α-glucosidase inhibitory activity from Cinnamosma macrocarpa Journal of Natural Products. 2007 Feb; 70(2):277-282.
  • Harinantenaina, L.; Harinantenaina, Y.; De Clercq, E. Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa JOURNAL OF NATURAL PRODUCTS. 2007 Feb; 70(2):277-282.
  • Liva Harinantenaina Yoshinori Asakawa, and De Clercq E Cinnamacrins A-D, Cinnafragrin D and Cytostatic Metabolites with alpha-Glucosidase Inhibitory Activity from Cinnamosma macrocarpa J. Nat. Prod.. 2007 Feb; 70 277-282.
  • Harinantenaina, L.; Quang, D.N.; Nishizawa, T.; Hashimoto, T. et al. Bioactive constituents from liverworts: Couparenoids and herbertenoids inhibit LPS induced iNOS in 264.7 RAW cells Phytomedicine. 2007 Feb; 14 486-491.
  • Harinantenaina, L.; Kida, S.; Asakawa, Y. Phytochemistry of three selected liverworts: Conocephalum conicum, Plagiochila barteri and P-terebrans ARKIVOC. 2007 Jan; 1 22-29.
  • Harinantenaina, L.; Asakawa, Y. Malagasy liverworts, source of new and biologically active compounds NATURAL PRODUCT COMMUNICATIONS. 2007 Jan; 2(6):701-709.
  • Harinantenaina Liva, Ritsu Kurata, Shigeru, Takaoka, Asakawa Yoshinori Chemical constituents of Malagasy liverworts: cyclomyltaylanoids from Bazzania madagassa. Phytochemistry. 2006 Dec; 67 2616-2622.
  • Harinantenaina, L.; Kurata, R.; Takaoka, S.; Asakawa, Y. Chemical constituents of Malagasy liverworts: Cyclomyltaylanoids from Bazzania madagassa PHYTOCHEMISTRY. 2006 Dec; 67(24):2616-2622.
  • Radulovic, N.; Mananjarasoa, E.; Harinantenaina, L.; Yoshinori, A. Essential oil composition of four Croton species from Madagascar and their chemotaxonomy BIOCHEMICAL SYSTEMATICS AND ECOLOGY. 2006 Aug; 34(8):648-653.
  • Niko Radulovic, Emilienne mananjarasoa, Harinantenaina Liva, Y. Asakawa Essential oil composition of four Croton species from Madagascar and their chemotaxonomy Biochem. Syst. Ecol.. 2006 Aug; 34 648-653.
  • Harinantenaina,Liva; Takaoka,Shigeru Cinnafragrins A-C, dimeric and trimeric drimane sesquiterpenoids from Cinnamosma fragrans, and structure revision of capsicodendrin JOURNAL OF NATURAL PRODUCTS. 2006 Aug; 69(8):1193-1197.
  • Harinantenaina Liva, Sigeru Takaoka Cinnafragrin A-C: Two dimeric and a trimeric drimane sesquiterpenoid from Cinnamosma fragrans. Structure revision of Capsicodendrin. J. Nat. Prod.. 2006 Aug; 69 1193-1197.
  • HARINANTENAINA, L.; Takahara, Y.; Nishizawa, T.; Kohchi, C. et al. Chemical Constituents of Malagasy Liverworts, Part V: Prenyl Bibenzyls and Clerodane Diterpenoids with Nitric Oxide Inhibitory Activity from Radula appressa and Thysananthus spathulistipus Chemical and Pharmaceutical Bulletin. 2006 Jul; 57 1046-1049.
  • Liva Harinantenaina,Yusuke Takahara, Takashi Nashizawa, Chie Kohchi, Gen-Ichiro Soma, Yoshinori Asakawa Chemical constituents of Malagasy liverworts Part V: Prenylated bibenzyls and clerodane diterpenes with nitric oxide inhibitory activity from Radula appressa and Thysananthus spathulistipus Chemical and Pharmaceutical Bulletin. 2006 Jul; 54 1046-1049.
  • Harinantenaina, L.; Tanaka, M.; Takaoka, S.; Uchida, M. et al. Momordica charantia constituents and antidiabetic screening of the isolated major compounds Chem. Pharm. Bull.. 2006 Jul; 54 1017-1021.
  • Harinantenaina, L.; Takahara, Y.; Nishizawa, T.; Kohchi, C. et al. Chemical constituents of malagasy liverworts, Part V: Prenyl bibenzyls and clerodane diterpenoids with nitric oxide inhibitory activity from Radula appressa and Thysananthus spathulistipus CHEMICAL & PHARMACEUTICAL BULLETIN. 2006 Jul; 54(7):1046-1049.
  • Liva Harinantenaina and Yoshinori Asakawa Malagasy liverworts, source of new and biologically active compounds Nat. Prod. Comm.. 2006 Jun; 2 701-709.
  • Harinantenaina, L.; Asakawa, Y. Identification of Cinnamosma Secondary Metabolites as alpha-glucosidase Inhibitors and Cytostatic Compounds. A Successful Example of the Application of Ethnobotany in Drug Discovery Journal of the Pharmaceutical Society of Japan. 2006 Apr; 126 96-99.
  • Quang, D.N.; Harinantenaina, L.; Nashizawa, T.; Hashimoto, T. et al. Inhibitory activity of nitric oxide production in RAW 264.7 cells of daldinals from the fungus Daldinia childiae and other metabolites isolated from inedible mushrooms J. Nat. Medicines. 2006 Apr; 60 303-307.
  • Liva Harinantenaina, Emilienne Mananjarasoa, Kasai R., Yamasaki K. A new acetylated eudesmane glucoside from Apodytes dimidiata Zeitshrift fur die Naturdoshung. 2006 Feb; 61b 113-115.
  • Harinantenaina, L.; Mananjarasoa, E.; Yamasaki, K. An acetylated eudesmane glucoside from Apodytes dimidiata growing in Madagascar ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES. 2006 Jan; 61(1):113-115.
  • Quang, D.N.; Harinantenaina, L.; Nishizawa, T.; Soma, K. et al. Inhibition of Nitric Oxide Production in RAW 264.7 Cells by Azaphilones from Xylariaceous Fungi Biol. Pharm. Bull.. 2006 Jan; 29 34-37.
  • Liva Harinantenaina, Dang Ngoc Quang, T. Nishizawa, K. Soma, Y. Asakawa Bis(bibenzyls) from liverworts inhibit LPS induced iNOS in 264.7 RAW cells J. Nat. Prod.. 2005 Dec; 68 1779-1781.
  • Harinantenaina, L.; Quang, D.N.; Takeshi, N.; Hashimoto, T. et al. Bis(bibenzyls) from liverworts inhibit lipopolysaccharide-induced inducible NOS in RAW 264.7 cells: A study of structure-activity relationships and molecular mechanism JOURNAL OF NATURAL PRODUCTS. 2005 Dec; 68(12):1779-1781.
  • Liva Harinantenaina, Yoshiaki Noma and Asakawa Yoshinori Penicillium sclerotiorum catalyzes the conversion of Herbertenediol into its dimers: Mastigophorenes A and B Chem. Pharm. Bull.. 2005 May; 53 256-257.
  • Harinantenaina, L.; Kurata, R.; Asakawa, Y. Chemical constituents of Malagasy liverworts, part III: Sesquiterpenoids from Bazzania decrescens and Bazzania madagassa CHEMICAL & PHARMACEUTICAL BULLETIN. 2005 May; 53(5):515-518.
  • Liva Harinantenaina, Ritsu Kurata, Asakawa Yoshinori Chemical constituents of Malagasy liverworts, Part III: Sesquiterpenoids from Bazzania decrescens and Bazzania madagassa Chem. Pharm. Bull.. 2005 May; 53 515-518.
  • Harinantenaina, L.; Noma, Y.; Asakawa, Y. Penicillium sclerotiorum catalyzes the conversion of herbertenediol into its dimers: Mastigophorenes A and B CHEMICAL & PHARMACEUTICAL BULLETIN. 2005 Feb; 53(2):256-257.
  • HARINANTENAINA, L. J. Nat. Prod.. 2005 Jan; 68 1779-1781.
  • Liva Harinantenaina, Asakawa Yoshinori Chemical constituents of Malagasy Liverworts, Part II: mastigophoric acid methyl ester of biogenetic interest from Mastigophora diclados Chem. Pharm. Bull.. 2004 Nov; 52 1382-13.
  • Harinantenaina, L.; Takaoka, S. Liva Harinantenaina, Yoshinori Asakawa. Chemical constituents of Isotachis aubertii (Isotachidaceae) collected from Madagascar Biochem. Syst. and Ecol.. 2004 Nov; 32 1073-1078.
  • Harinantenaina, L.; Asakawa, Y. Chemical constituents of Malagasy liverworts, Part II: Mastigophoric acid methyl ester of biogenetic interest from Mastigophora diclados (Lepicoleaceae subf. Mastigophoroideae) CHEMICAL & PHARMACEUTICAL BULLETIN. 2004 Nov; 52(11):1382-1384.
  • HARINANTENAINA, L. Biochem. Syst. Ecol.. 2004 Jan; 32 1073-1078.
  • Harinantenaina, L.; Kasai, R.; Yamasaki, K. A new ent-kaurane diterpene glucoside from Cussonia bojeri Seem Chem. Pharm. Bull.. 2002 Dec; 50 1122-1124.
  • Mananjarasoa, E.; Ochi, H.; Harinantenaina, L.; Kasai, R. et al. A new secoiridoid glucoside from a malagasy medicinal plant, Cassinopsis chapieleri Natural Medicines. 2002 Oct; 56(5):204-207.
  • Harinantenaina, L.; Kasai, R.; Kasai, K. ent-Kaurane diterpenoid glycosides from a Malagasy endemic plant, Cussonia vantsilana PHYTOCHEMISTRY. 2002 Oct; 61(4):367-372.
  • Harinantenaina, L.; Kasai, R.; Rakotovao, M.; Yamasaki, K. Iridoid glucosides of a Malagasy medicinal plant, Ophiocolea floribunda (Bignoniaceae) Natural Medicines. 2002 Oct; 56 217-217.
  • Harinantenaina, L.; Kasai, R.; Rakotovao, M.; Yamasaki, K. Iridoid glucosides from a malagasy medicinal plant, Ophiocolea floribunda Natural Medicines. 2002 Oct; 56(5):217.
  • Liva Harinantenaina, Kasai R., Yamasaki K. Ent-kaurane diterpenoid glycosides from Cussonia vantsilana Phytochemistry. 2002 Oct; 61 367-372.
  • Harinantenaina, L.; Kasai, R.; Yamasaki, K. Cussosaponins A-E, triterpene saponins from the leaves of Cussonia racemosa, a Malagasy endemic plant CHEMICAL & PHARMACEUTICAL BULLETIN. 2002 Sep; 50(9):1290-1293.
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