Leslie Newman, PhD
Professional Interests
My research interests include studying how genetic factors affect an individual’s response to drugs as well as understanding the neurochemical changes that cause and occur during drug addiction. My teaching interests are in Molecular and Cellular Pharmacology, Drugs of Addiction, Toxicology and Scientific Communication. My teaching involves implementing technology and active learning in the classroom to help students develop their critical thinking skills and apply what they learn to real world applications. Additionally, I am interested in courses that help students to develop effective written and oral communication skills involving the expression of their own ideas and research as well as interpreting and communicating other areas of scientific information.
Journal Articles
Webb A, Papp AC, Curtis A, Newman LC, Pietrzak M, Seweryn M, Handelman SK, Rempala GA, Wang D, Graziosa E, Tyndale RF, Lerman C, Kelsoe JR, Mash DC, Sadee W. RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles. BMC Genomics. 2015 Nov 23;16:990. doi: 10.1186/s12864-015-2207-8. PMID: 26597164; PMCID: PMC4657279.
Suhy A, Hartmann K, Newman L, Papp A, Toneff T, Hook V, Sadee W. Genetic variants affecting alternative splicing of human cholesteryl ester transfer protein. Biochem Biophys Res Commun. 2014 Jan 24;443(4):1270-4. doi: 10.1016/j.bbrc.2013.12.127. Epub 2014 Jan 3. PMID: 24393849; PMCID: PMC3929938.
Smith RM, Webb A, Papp AC, Newman LC, Handelman SK, Suhy A, Mascarenhas R, Oberdick J, Sadee W. Whole transcriptome RNA-Seq allelic expression in human brain. BMC Genomics. 2013 Aug 22;14:571. doi: 10.1186/1471-2164-14-571. PMID: 23968248; PMCID: PMC3765493.
Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W. Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. PLoS One. 2012;7(3):e31930. doi: 10.1371/journal.pone.0031930. Epub 2012 Mar 5. PMID: 22403620; PMCID: PMC3293889.