Julie Johnson, PharmD
Professor of Medicine (Internal Medicine) & Pharmaceutics and Pharmacology
Director, Clinical and Translational Science Institute
Professional Interests
Biography
Additional Positions:
- Professor of Medicine (Internal Medicine) and Pharmacy (Outcomes and Translational Science)
- Dr. Samuel T. Lois Felts Mercer Professorship of Medicine and Pharmacology, The Ohio State University College of Medicine
- Director, Clinical and Translational Science Institute
- Associate Dean for Clinical and Translational Research, The Ohio State University College of Medicine
- Associate Vice President of Research, The Ohio State University
A native Ohioan, Dr. Johnson earned her Bachelor of Science in Pharmacy from The Ohio State University, followed by her Doctor of Pharmacy from the University of Texas at Austin and the University of Texas Health Science Center at San Antonio. She returned to Ohio State to complete a postdoctoral fellowship in pharmacokinetics/cardiovascular pharmacology.
From 1998 - 2023, Dr. Johnson served on the faculty at the University of Florida (UF), where she was a Distinguished Professor of Pharmacy and Medicine and became the first female dean of the College of Pharmacy, serving from 2013 to 2022. Under her leadership, the University of Florida College of Pharmacy grew its faculty by 90% and rose from No. 14 to No. 5 in the U.S. News & World Report rankings of the best pharmacy colleges in the nation. The college’s annual research funding also increased from approximately No. 20 to No. 3 among the nation’s top colleges of pharmacy and saw the highest percentage of under-represented, minority students among professional degree programs at the University of Florida. At UF she also served as a department chair, Founding Director of the Center for Pharmacogenomics and Founding Director of the UF Health Precision Medicine Program.
An internationally recognized leader in clinical pharmacology, pharmacogenomics and genomic medicine, Dr. Johnson has an extensive record of clinical and translational research, focusing on cardiovascular pharmacogenomics and the implementation of precision medicine approaches into clinical practice. She has a long record of funding from the National Institutes of Health (NIH) and has secured approximately $55 million in research funding as a PI. She has written more than 330 peer-reviewed original research articles and was named Clarivate Analytics Highly Cited Researcher, an accomplishment held by just 1 in 1,000 scientists globally whose publications rank in the top 1% of citations in the previous decade.
Dr. Johnson also serves as the director of Ohio State’s Center for Clinical and Translational Science and is the principal investigator of a seven-year $37.9 million Clinical and Translation Science Award from the National Institutes of Health.
Education
- 1987-1989, Postdoctoral Fellowship in Pharmacokinetics/Clinical Pharmacology, The Ohio State University
- 1987, PharmD Pharmacy, The University of Texas at Austin and The University of Texas Health Science Center at San Antonio
- 1985, BS Pharmacy, The Ohio State University
Honors
- 2025, Oscar B Hunter Career Award in Therapeutics, American Society for Clinical Pharmacology and Therapeutics
- 2025, Mercer University G. Van Greene Distinguished Lecturer. Mercer University College of Pharmacy
- 2024, University of California San Francisco, School of Pharmacy Commencement Speaker
- 2023, Coy W. Waller Distinguished Lecturer, School of Pharmacy, University of Mississippi
- 2023, Mentoring Award, American Society for Clinical Pharmacology and Therapeutics
- 2022, University of Florida Presidential Award for Outstanding Service
- 2022, Texas A&M University College of Pharmacy Commencement Speaker
- 2022, Kremers Lecturer, University of Wisconsin School of Pharmacy
- 2021, Kremers Lecturer, University of Wisconsin School of Pharmacy
- 2021, Rawls Palmer Progress in Medicine Award, American Society for Clinical Pharmacology and Therapeutics
- 2020, American Association for the Advancement of Science, elected Fellow
- 2019, American College of Clinical Pharmacy Paul Parker Medal recipient, for Distinguished Contributions to the Profession of Pharmacy
- 2019, American College of Clinical Pharmacology Distinguished Investigator Award
- 2019, Commencement speaker, University of Texas at Austin College of Pharmacy
- 2019, Commencement speaker, University of Michigan College of Pharmacy
- 2017 & 2018, Clarivate Analytics Highly Cited Scientist in Cross Discipline
- 2018, Charles M Gruber Distinguished Lecturer. Thomas Jefferson University Sidney Kimmel Medical College
- 2018, Milap Nahata Distinguished Lecturer, The Ohio State University College of Pharmacy
- 2017, Varro E. Tyler Distinguished Lecturer, Purdue University College of Pharmacy
- 2017, Leon Goldberg Endowed Lectureship, University of Chicago Department of Medicine
- 2017, Grant Wilkinson Distinguished Lectureship, Vanderbilt University College of Medicine
- 2015 & 2016, Thomson Reuters Highly Cited Scientist in Pharmacology and Toxicology
- 2016, Volwiler Research Achievement Award, American Association of Colleges of Pharmacy
- 2016, Commencement Speaker, University of California at San Diego School of Pharmacy
- 2016, William B. Abrams Lectureship Award, American Society for Clinical Pharmacology and Therapeutics and The US Food and Drug Administration
- 2015, Mentoring Award, Functional Genomics and Translational Biology Council of the American Heart Association
- 2015, Southeastern Universities Research Association Distinguished Scientist Award
- 2014, National Academy of Medicine (formerly Institute of Medicine) member
- 2014, Gerhard Levy Distinguished Lectureship in Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Science, University of Buffalo
- 2014, Honorary Fellow Award, American College of Clinical Pharmacology
- 2013, University of North Carolina Institute for Pharmacogenomics and Individualized Therapy Clinical Service Award
- 2013-2015, University of Florida Research Foundation Professorship Award, University of Florida
- 2013, The Sebok Pharmacy Lecture, Raabe College of Pharmacy, Ohio Northern University
- 2010, Distinguished Investigator Award, American College of Clinical Pharmacy Cardiology Practice and Research Network
- 2010, Russell Miller Award for Contribution to the Literature, American College of Clinical Pharmacy
- 2010, Gutkey Memorial Lecture and Dean’s Convocation, University of Colorado School of Pharmacy
- 2010, Loius C. Littlefield Research Excellence Day Plenary Speaker, University of Texas at Austin
- 2010, Julius Koch Memorial Lecturer, University of Pittsburgh College of Pharmacy
- 2009, Fellow, American Heart Association; Functional Genomics and Translational Biology Council
- 2009, Therapeutic Frontiers Award, American College of Clinical Pharmacy
- 2008, Robert G. Leonard Memorial Lecture Award, Texas Society of Health System Pharmacists and University of Texas at Austin
- 2008, First Tennessee Chair of Excellence Visiting Professor, University of Tennessee College of Pharmacy
- 2007, Paul Dawson Biotechnology Research Award, American Association of Colleges of Pharmacy
- 2007, University of Florida Faculty Achievement Recognition Award
- 2006, David E. Guttman Memorial Lecturer, University of Kentucky College of Pharmacy
- 2005, Ohio State University College of Pharmacy Distinguished Alumni Award
- 2004-2013, V. Ravi Chandran Professor of Pharmaceutical Sciences, endowed professorship
- 2004-2006, University of Florida Research Foundation Professorship Award
- 2004, Leon I. Goldberg Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics
- 2003, 31st Annual Albert Ebert Lecturer, University of Illinois-Chicago College of Pharmacy
- 2003, Philip C. and Ethel R. Ashby Lecturer, University of Oklahoma College of Pharmacy
- 2001, Outstanding Faculty of the Year, Working Professional Pharm.D. Program, University of Florida
- 2000-2004, FDA Committee Appointee – Nonprescription Drug Advisory Committee
- 2000-2003, Elected Officer (Regent) – American College of Clinical Pharmacy Board of Regents
- 1997, The Ohio State University William Oxley Thompson Alumni Award
- 1996, The Ohio State University William Oxley Thompson Alumni Award
Publications
- In vitro comparative analysis of metabolic capabilities and inhibitory profiles of selected CYP2D6 alleles on tramadol metabolism, Clinical and Translational Science. 2025 Feb | journal-article. doi: 10.1111/cts.70059.
- Local ancestry informed GWAS of warfarin dose requirement in African Americans identifies a novel CYP2C19 splice QTL, Medrxiv. 2025 Jan | other. doi: 10.1101/2025.03.03.25323247.
- Pharmacogenetics: Opportunities for the All of Us Research Program and Other Large Data Sets to Advance the Field, Annual Review of Pharmacology and Toxicology. 2025 Jan | book. doi: 10.1146/annurev-pharmtox-061724-080718.
- Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry, Blood Advances. 2024 Oct | journal-article. doi: 10.1182/bloodadvances.2024014227.
- Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the
IGNITE ADOPT PGx investigators, Clinical and Translational Science. 2024 Aug | journal-article. doi: 10.1111/cts.70005. - Rationale and design for a pragmatic randomized trial to assess
gene‐based prescribing forSSRIs in the treatment of depression, Clinical and Translational Science. 2024 Jun | journal-article. doi: 10.1111/cts.13822. - CYP2C19 Genotype Is Associated With Adverse Cardiovascular Outcomes in Black Patients Treated With Clopidogrel Undergoing Percutaneous Coronary Intervention, Journal of the American Heart Association. 2024 Jan | journal-article. doi: 10.1161/JAHA.123.033791.
- Circulating microRNA Biomarkers of Thiazide Response in Hypertension, Journal of the American Heart Association. 2024 Jan | journal-article. doi: 10.1161/JAHA.123.032433.
- Effectiveness of Clopidogrel vs Alternative P2Y12 Inhibitors Based on the ABCD-GENE Score, Journal of the American College of Cardiology. 2024 Jan | journal-article. doi: 10.1016/j.jacc.2024.02.015.
- Integrated metabolomics analysis reveals mechanistic insights into variability in blood pressure response to thiazide diuretics and beta blockers, Clinical and Translational Science. 2024 Jan | journal-article. doi: 10.1111/cts.13816.
- Recurrent stroke prediction by applying a stroke polygenic risk score in the Japanese population, Medrxiv. 2024 Jan | other. doi: 10.1101/2024.06.17.24309034.
- Use of CYP2D6 Inhibitors with CYP2D6 Opioids: Association with Emergency Department Visits for Pain, Clinical Pharmacology and Therapeutics. 2024 Jan | journal-article. doi: 10.1002/cpt.3314.
- A Pharmacogenetics-Based Approach to Managing Gastroesophageal Reflux Disease: Current Perspectives and Future Steps, Pharmacogenomics and Personalized Medicine. 2023 Jan | journal-article. doi: 10.2147/PGPM.S371994.
- Evaluation of Potential Racial Disparities in CYP2C19-Guided P2Y12 Inhibitor Prescribing After Percutaneous Coronary Intervention, Clinical Pharmacology and Therapeutics. 2023 Jan | journal-article. doi: 10.1002/cpt.2776.
- Use of a multi-gene pharmacogenetic panel reduces adverse drug effects, Cell Reports Medicine. 2023 Jan | journal-article. doi: 10.1016/j.xcrm.2023.101021.
- Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke, Neurology. 2022 Oct | journal-article. doi: 10.1212/wnl.0000000000201006.
- A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence, Clinical and Translational Science. 2022 Jan | journal-article. doi: 10.1111/cts.13294.
- Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis, Frontiers in Physiology. 2022 Jan | journal-article. doi: 10.3389/fphys.2022.909870.
- CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings, Journal of the American Heart Association. 2022 Jan | journal-article. doi: 10.1161/JAHA.121.024159.
- CYP2D6 pharmacogenetics and phenoconversion in personalized medicine, Expert Opinion on Drug Metabolism and Toxicology. 2022 Jan | journal-article. doi: 10.1080/17425255.2022.2160317.
- Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update, Clinical Pharmacology and Therapeutics. 2022 Jan | journal-article. doi: 10.1002/cpt.2526.
- Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension, Frontiers in Genetics. 2022 Jan | journal-article. doi: 10.3389/fgene.2022.836636.
- Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension, Contemporary Clinical Trials. 2022 Jan | journal-article. doi: 10.1016/j.cct.2022.106813.
- Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study, Genes. 2022 Jan | journal-article. doi: 10.3390/genes13071260.
- Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-Site, Real-World Investigation, Clinical Pharmacology and Therapeutics. 2022 Jan | journal-article. doi: 10.1002/cpt.2612.
- Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators, Clinical and Translational Science. 2022 Jan | journal-article. doi: 10.1111/cts.13376.
- Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients, Metabolites. 2022 Jan | journal-article. doi: 10.3390/metabo12090783.
- Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations, Journal of Thrombosis and Haemostasis. 2022 Jan | journal-article. doi: 10.1111/jth.15698.
- Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients, Clinical and Translational Science. 2022 Jan | journal-article. doi: 10.1111/cts.13396.
- Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (Nature, (2022), 611, 7934, (115-123), 10.1038/s41586-022-05165-3), Nature. 2022 Jan | journal-article. doi: 10.1038/s41586-022-05492-5.
- Stroke genetics informs drug discovery and risk prediction across ancestries, Nature. 2022 Jan | journal-article. doi: 10.1038/s41586-022-05165-3.
- Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles, Clinical Pharmacology and Therapeutics. 2022 Jan | journal-article. doi: 10.1002/cpt.2549.
- β1-receptor polymorphisms and junctional ectopic tachycardia in children after cardiac surgery, Clinical and Translational Science. 2022 Jan | journal-article. doi: 10.1111/cts.13178.
- A hybrid implementation-effectiveness randomized trial of CYP2D6-guided postoperative pain management, Genetics in Medicine. 2021 Jan | journal-article. doi: 10.1038/s41436-020-01050-4.
- Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies, Clinical Pharmacology and Therapeutics. 2021 Jan | journal-article. doi: 10.1002/cpt.2355.
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing, Clinical Pharmacology and Therapeutics. 2021 Jan | journal-article. doi: 10.1002/cpt.2015.
- Determining the potential clinical value of panel-based pharmacogenetic testing in patients with chronic pain or gastroesophageal reflux disease, Pharmacogenomics Journal. 2021 Jan | journal-article. doi: 10.1038/s41397-021-00244-6.
- Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network, Genetics in Medicine. 2021 Jan | journal-article. doi: 10.1038/s41436-021-01118-9.
- Evaluating an interactive teaching approach with personal genotyping to provide pharmacy students with a knowledge base for clinical pharmacogenetics, Jaccp Journal of the American College of Clinical Pharmacy. 2021 Jan | journal-article. doi: 10.1002/jac5.1335.
- Genetic Contributions to Early and Late Onset Ischemic Stroke, Medrxiv. 2021 Jan | other. doi: 10.1101/2021.11.06.21265795.
- Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality, European Heart Journal. 2021 Jan | journal-article. doi: 10.1093/eurheartj/ehab107.
- Genome-wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores, Medrxiv. 2021 Jan | other. doi: 10.1101/2021.09.08.21263225.
- How to Integrate CYP2D6 Phenoconversion Into Clinical Pharmacogenetics: A Tutorial, Clinical Pharmacology and Therapeutics. 2021 Jan | journal-article. doi: 10.1002/cpt.2354.
- Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention, Clinical Pharmacology and Therapeutics. 2021 Jan | journal-article. doi: 10.1002/cpt.2039.
- Metabolomics signature of plasma renin activity and linkage with blood pressure response to beta blockers and thiazide diuretics in hypertensive european american patients, Metabolites. 2021 Jan | journal-article. doi: 10.3390/metabo11090645.
- Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing, Genetics in Medicine. 2021 Jan | journal-article. doi: 10.1038/s41436-021-01269-9.
- Race-Specific Comparisons of Antihypertensive and Metabolic Effects of Hydrochlorothiazide and Chlorthalidone, American Journal of Medicine. 2021 Jan | journal-article. doi: 10.1016/j.amjmed.2020.12.015.
- Strategies to integrate genomic medicine into clinical care: Evidence from the IGNITE network, Journal of Personalized Medicine. 2021 Jan | journal-article. doi: 10.3390/jpm11070647.
- Tribute to Professor Hartmut Derendorf - 1953 to 2020: Driving force in Clinical Pharmacology and Mentor Extraordinaire, Clinical Pharmacology and Therapeutics. 2021 Jan | journal-article. doi: 10.1002/cpt.2193.
- A Scoping Review of the Evidence Behind Cytochrome P450 2D6 Isoenzyme Inhibitor Classifications, Clinical Pharmacology and Therapeutics. 2020 Jan | journal-article. doi: 10.1002/cpt.1768.
- Association of factor v leiden with subsequent atherothrombotic events: A GENIUS-CHD study of individual participant data, Circulation. 2020 Jan | journal-article. doi: 10.1161/CIRCULATIONAHA.119.045526.
- Clinical Pharmacology Education – The Decade Ahead, Clinical Pharmacology and Therapeutics. 2020 Jan | journal-article. doi: 10.1002/cpt.1652.
- Clinical Utility of Pharmacogene Panel-Based Testing in Patients Undergoing Percutaneous Coronary Intervention, Clinical and Translational Science. 2020 Jan | journal-article. doi: 10.1111/cts.12729.
- Combination antihypertensive therapy prescribing and blood pressure control in a real-world setting, American Journal of Hypertension. 2020 Jan | journal-article. doi: 10.1093/ajh/hpz196.
- Correction: Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection (Genetics in Medicine, (2020), 22, 11, (1898-1902), 10.1038/s41436-020-0894-2), Genetics in Medicine. 2020 Jan | journal-article. doi: 10.1038/s41436-020-0931-1.
- Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data, Pharmacogenomics Journal. 2020 Jan | journal-article. doi: 10.1038/s41397-020-0162-5.
- Design and early implementation successes and challenges of a pharmacogenetics consult clinic, Journal of Clinical Medicine. 2020 Jan | journal-article. doi: 10.3390/jcm9072274.
- Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection, Genetics in Medicine. 2020 Jan | journal-article. doi: 10.1038/s41436-020-0894-2.
- Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores, Cpt Pharmacometrics and Systems Pharmacology. 2020 Jan | journal-article. doi: 10.1002/psp4.12563.
- How to Transition from Single-Gene Pharmacogenetic Testing to Preemptive Panel-Based Testing: A Tutorial, Clinical Pharmacology and Therapeutics. 2020 Jan | journal-article. doi: 10.1002/cpt.1912.
- Pharmacogenetic factors affecting β-blocker metabolism and response, Expert Opinion on Drug Metabolism and Toxicology. 2020 Jan | journal-article. doi: 10.1080/17425255.2020.1803279.
- Response to: Heterogeneous Treatment Response by Race Cannot Be Claimed in the Absence of Evidence, American Journal of Hypertension. 2020 Jan | journal-article. doi: 10.1093/ajh/hpz168.
- Sorting nexin 1 loss results in increased oxidative stress and hypertension, FASEB Journal. 2020 Jan | journal-article. doi: 10.1096/fj.201902448R.
- The Patient-Centered Future of Clinical Pharmacology, Clinical Pharmacology and Therapeutics. 2020 Jan | journal-article. doi: 10.1002/cpt.1681.
- What will be your legacy in pharmacy? How will you be a Paul Parker?, Jaccp Journal of the American College of Clinical Pharmacy. 2020 Jan | journal-article. doi: 10.1002/jac5.1195.
- A case for genotype-guided pain management, Pharmacogenomics. 2019 Jan | journal-article. doi: 10.2217/pgs-2019-0068.
- Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease, Journal of Clinical Hypertension. 2019 Jan | journal-article. doi: 10.1111/jch.13429.
- Association of chromosome 9p21 with subsequent coronary heart disease events: A GENIUS-CHD study of individual participant data, Circulation Genomic and Precision Medicine. 2019 Jan | journal-article. doi: 10.1161/CIRCGEN.119.002471.
- CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial, Genetics in Medicine. 2019 Jan | journal-article. doi: 10.1038/s41436-018-0431-8.
- Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene–drug pairs across ambulatory care settings, Genetics in Medicine. 2019 Jan | journal-article. doi: 10.1038/s41436-019-0500-7.
- Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals, Clinical Pharmacology and Therapeutics. 2019 Jan | journal-article. doi: 10.1002/cpt.1323.
- Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies, European Journal of Pharmaceutical Sciences. 2019 Jan | journal-article. doi: 10.1016/j.ejps.2019.02.013.
- Essential Characteristics of Pharmacogenomics Study Publications, Clinical Pharmacology and Therapeutics. 2019 Jan | journal-article. doi: 10.1002/cpt.1279.
- Gene variants at loci related to blood pressure account for variation in response to antihypertensive drugs between black and white individuals: Genomic precision medicine may dispense with ethnicity, Hypertension. 2019 Jan | journal-article. doi: 10.1161/HYPERTENSIONAHA.118.12177.
- Generic Cost-Effectiveness Models: A Proof of Concept of a Tool for Informed Decision-Making for Public Health Precision Medicine, Public Health Genomics. 2019 Jan | journal-article. doi: 10.1159/000500725.
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting, Neurology. 2019 Jan | journal-article. doi: 10.1212/WNL.0000000000006851.
- Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response, Scientific Reports. 2019 Jan | journal-article. doi: 10.1038/s41598-019-53345-5.
- Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies), Journal of the American Heart Association. 2019 Jan | journal-article. doi: 10.1161/JAHA.119.013115.
- Genome-wide association analysis of common genetic variants of resistant hypertension, Pharmacogenomics Journal. 2019 Jan | journal-article. doi: 10.1038/s41397-018-0049-x.
- Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans, Clinical and Translational Science. 2019 Jan | journal-article. doi: 10.1111/cts.12643.
- Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers, Plos One. 2019 Jan | journal-article. doi: 10.1371/journal.pone.0221957.
- Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing, Genetics in Medicine. 2019 Jan | journal-article. doi: 10.1038/s41436-019-0484-3.
- Novel Implementation of Genotype-Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial, Clinical and Translational Science. 2019 Jan | journal-article. doi: 10.1111/cts.12589.
- Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans with Uncomplicated Hypertension, American Journal of Hypertension. 2019 Jan | journal-article. doi: 10.1093/ajh/hpz022.
- Qualitative study of system-level factors related to genomic implementation, Genetics in Medicine. 2019 Jan | journal-article. doi: 10.1038/s41436-018-0378-9.
- Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study, Neurology. 2019 Jan | journal-article. doi: 10.1212/WNL.0000000000007001.
- Subsequent Event Risk in Individuals With Established Coronary Heart Disease, Circulation Genomic and Precision Medicine. 2019 Jan | journal-article. doi: 10.1161/CIRCGEN.119.002470.
- β2-Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies, Journal of Clinical Pharmacology. 2019 Jan | journal-article. doi: 10.1002/jcph.1443.
- AMCP Partnership forum: Managing care in the wave of precision medicine, Journal of Managed Care and Specialty Pharmacy. 2018 Jan | journal-article. doi: 10.18553/jmcp.2018.24.7.583.
- Blood pressure signature genes and blood pressure response to thiazide diuretics: Results from the PEAR and PEAR-2 studies, BMC Medical Genomics. 2018 Jan | journal-article. doi: 10.1186/s12920-018-0370-x.
- Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention, Journal of Translational Medicine. 2018 Jan | journal-article. doi: 10.1186/s12967-018-1469-8.
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes, Nature Communications. 2018 Jan | journal-article. doi: 10.1038/s41467-018-07340-5.
- Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses), Circulation Genomic and Precision Medicine. 2018 Jan | journal-article. doi: 10.1161/CIRCGEN.117.001854.
- Genome wide association study identifies the HMGCS2 locus to be associated with chlorthalidone induced glucose increase in hypertensive patients, Journal of the American Heart Association. 2018 Jan | journal-article. doi: 10.1161/JAHA.117.007339.
- Genome-wide association approach identified novel genetic predictors of heart rate response to β-blockers, Journal of the American Heart Association. 2018 Jan | journal-article. doi: 10.1161/JAHA.117.006463.
- Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes, Pharmacogenomics Journal. 2018 Jan | journal-article. doi: 10.1038/tpj.2016.67.
- Implementation of Standardized Clinical Processes for TPMT Testing in a Diverse Multidisciplinary Population: Challenges and Lessons Learned, Clinical and Translational Science. 2018 Jan | journal-article. doi: 10.1111/cts.12533.
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes, Nature Genetics. 2018 Jan | journal-article. doi: 10.1038/s41588-018-0058-3.
- Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention, Jacc Cardiovascular Interventions. 2018 Jan | journal-article. doi: 10.1016/j.jcin.2017.07.022.
- Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy, Clinical Pharmacology and Therapeutics. 2018 Jan | journal-article. doi: 10.1002/cpt.1006.
- Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine, Expert Opinion on Drug Metabolism and Toxicology. 2018 Jan | journal-article. doi: 10.1080/17425255.2018.1461835.
- Publisher correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes(Nature Genetics, (2018) 50, 4, (524-537), 10.1038/s41588-018-0058-3), Nature Genetics. 2018 Jan | journal-article. doi: 10.1038/s41588-019-0449-0.
- Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects, Clinical Pharmacology and Therapeutics. 2018 Jan | journal-article. doi: 10.1002/cpt.1048.
- Sphingolipid metabolic pathway impacts thiazide diuretics blood pressure response: Insights from genomics, metabolomics, and lipidomics, Journal of the American Heart Association. 2018 Jan | journal-article. doi: 10.1161/JAHA.117.006656.
- Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide, Pharmacogenetics and Genomics. 2018 Jan | journal-article. doi: 10.1097/FPC.0000000000000353.
- Whole Transcriptome Profiling: An RNA-Seq Primer and Implications for Pharmacogenomics Research, Clinical and Translational Science. 2018 Jan | journal-article. doi: 10.1111/cts.12511.
- Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension, Journal of Clinical Hypertension. 2017 Jan | journal-article. doi: 10.1111/jch.13094.
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update, Clinical Pharmacology and Therapeutics. 2017 Jan | journal-article. doi: 10.1002/cpt.668.
- Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms, Nature Genetics. 2017 Jan | journal-article. doi: 10.1038/ng.3874.
- Genetic variants associated with uncontrolled blood pressure on thiazide diuretic/β-blocker combination therapy in the PEAR (Pharmacogenomic Evaluation Of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) trials, Journal of the American Heart Association. 2017 Jan | journal-article. doi: 10.1161/JAHA.117.006522.
- Genetic variation at 16q24.2 is associated with small vessel stroke, Annals of Neurology. 2017 Jan | journal-article. doi: 10.1002/ana.24840.
- Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated with Thiazide Diuretics Blood Pressure Response, Circulation Cardiovascular Genetics. 2017 Jan | journal-article. doi: 10.1161/CIRCGENETICS.116.001404.
- Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide, Hypertension. 2017 Jan | journal-article. doi: 10.1161/HYPERTENSIONAHA.116.08267.
- Genome-wide study of resistant hypertension identified from electronic health records, Plos One. 2017 Jan | journal-article. doi: 10.1371/journal.pone.0171745.
- Impact of Selection Bias on Estimation of Subsequent Event Risk, Circulation Cardiovascular Genetics. 2017 Jan | journal-article. doi: 10.1161/CIRCGENETICS.116.001616.
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