Natural products have always played a key role for medicinal chemists in the process of drug discovery. Employing the structural scaffolds and biological activity of these compounds as a starting point, our group intends to use synthetic chemistry as a tool to probe biological problems. Specifically, Dr. Fuch’s lab utilizes synthetic methods to prepare these bioactive natural products and their analogues, gains insight into the structure–activity relationships of ligand/receptor systems, and investigates biosynthetic pathways. Ultimately, the goal is not simply to prepare these natural products, but to improve upon their activity and pharmacological profiles.
- 2007, Postdoctoral Fellow, The Scripps Research Institute, Medicinal/Organic Chemistry
- 2005, PhD, Pennsylvania State University, Organic Chemistry
- 1998, BS, cum laude, University Honors, Honors in Chemistry, University of Toledo, Chemistry