April 27, 2017
The Ohio State University College of Pharmacy held its 12th annual Research Day on Thursday, April 6, 2017, at the Drake Union to celebrate innovative research in the college.
Research Day provides an opportunity for students, research staff, and faculty of the College of Pharmacy to present their work and network. A poster competition also gives students the opportunity to win cash prizes for their research. This year, more than 70 presenters displayed their research findings.
After the poster presentation, Dr. John Byrd, the D. Warren Brown Chair of Leukemia Research in the Ohio State College of Medicine, presented on Directing Multiple Therapeutic Strategies toward On Targets of Ibrutinib.
Dr. Byrd’s research accomplishments over the past 10 years relate best to work done between the laboratory and clinic (translational work) with several different therapeutic agents active in CLL and related leukemia and lymphoma. As a consequence of Dr. Byrd’s detailed laboratory and clinical work, therapeutic agents such as rituximab, alemtuzumab, and recently flavopiridol have been identified as effective agents for CLL. In particular, Dr. Byrd has and continues to be very active in development of therapeutic antibodies and other targeted agents because of his desire to work on non-toxic therapies for the treatment of leukemia.
After Dr. Byrd’s presentation, Dr. Cynthia Carnes, senior associate dean for research and graduate education, presented the awards to the top-scored presenters.
“Research Day was a success due to the collaboration across the college. Participants receive great value out of the interactions during the poster presentations. I received numerous comments on the high-quality of the presentations and the impressive work that is happening at the college,” said Dr. Carnes.
This year’s poster winners are listed by category below:
First place – Shuiying Hu
TYROSINE PHOSPHORYLATION MEDIATED REGULATION OF OCT1 AND MATE1 FUNCTION
Shuiying Hu, Navjot Pabla, Alice A. Gibson, Alix F Leblanc, Kristen W Hong, Sharyn D. Baker, and Alex Sparreboom, Division of Pharmaceutics, College of Pharmacy, The Ohio State University
First place – Daniel Binzel
RNA NANOTECHNOLOGY FOR THE SPECIFIC TARGETING AND DELIVERY OF MIRNA FOR INHIBITION OF PROSTATE CANCER
Daniel W. Binzel1, Yi Shu2, Hui Li1, Meiyan Sun3, Qunshu Zhang3, Dan Shu1, Bin Guo3, Peixuan Guo1* 1College of Pharmacy; College of Medicine/Department of Physiology ＆ Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University; 2Nanobiotechnology Center; Markey Cancer Center; Department of Pharmaceutical Sciences; University of Kentucky, Lexington, KY; 3Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND
Second place – Yuntao Bai
MITIGATION OF ACUTE KIDNEY INJURY BY TARGETING FGF (R) SIGNALING PATHWAY
Yuntao Bai1, Ji Young Kim1, Navjot Pabla1 Pharmaceutics & Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University
Residents and fellows:
First place – Ayoung Kim
IMPACT OF PHARMACIST-LED INTERVENTIONS IN THE MANAGEMENT OF PREDIABETES IN MEDICALLY UNDERSERVED PATIENTS
Ayoung Kim1, Kristina W. Naseman1, Junan Li1College of Pharmacy
Second place – Kriss Petrovskis
IMPLEMENTATION OF QUALITY IMPROVEMENT METHODOLOGIES TO REDUCE WHITE BAGGING WASTE IN A PEDIATRIC INFUSION CLINIC
Kriss J. Petrovskis1,2, Patrick T. Collins1, Chet G. Kaczor1, Vinita B. Pai1,2, Marjorie V. Neidecker2, Jim L. Jones1, Jenna M. Merandi1, Don A. Buckingham3, Michael A. Storey1. 1Nationwide Children's Hospital, The Ohio State University College of Pharmacy, Nationwide Children's Hospital, Quality Improvement Services
Undergraduate and PharmD students:
First place (tie) – Emily Ciborek
A RESEARCH PROPOSAL: A NOVEL REDESIGN OF IMPLANTED CENTRAL LINES FOR IMPROVING THE QUALITY OF LIFE OF PATIENTS
Emily L. Ciborek and Sylvan Frank College of Pharmacy, The Ohio State University
First place (tie) – Kristen Hong
ZEBRAFISH AS A MODEL ORGANISM IN THE STUDY OF ORGANIC CATION TRANSPORTERS
Kristen W. Hong, Alix F. Leblanc, Shuiying Hu, Navjot Pabla, Alice A Gibson, Alex Sparreboom College of Pharmacy, The Ohio State University
Clinical and translational science:
First place – Jae Yoon Jeon
TP-0903, A NOVEL FLT3 INHIBITOR WITH ACTIVITY IN DRUG RESISTANT FLT3-ITD+ AML
Jae Yoon Jeon1, Il-Kyoo Park1, Daelynn R Buelow1, William Blum2, Sharyn D Baker Divisions of 1Pharmaceutics and Pharmaceutical Chemistry and 2Hematology, The Ohio State University & Comprehensive Cancer Center
First place (tie) – Mingqing Chen
ROLE OF ORGANIC ANION TRANSPORTING POLYPEPTIDE (OATP) 2B1 IN TYROSINE KINASE INHIBITORS (TKIS) DISPOSITION
Mingqing Chen, Alice A. Gibson, Sharyn D. Baker, Alex Sparreboom Division of Pharmaceutics, College of Pharmacy and Comprehensive Cancer Center
First place (tie) – Sophia Liva
COMBINED HDAC INHIBITION (AR-42) AND SELECTIVE ANDROGEN RECEPTOR MODULATOR (ENOBOSARM, GTX-024) ADMINISTRATION AS CANCER-RELATED CACHEXIA THERAPY
Sophia G. Liva2, Yu-Chou Tseng1, Sally E. Henderson1, YC Ku1, Jason A. Benedict4, Samuel K. Kulp1, Tony Bekaii-Saab3*, Erin E. Talbert6, Denis C. Guttridge6, Ching-Shih Chen1,5 and Christopher C. Coss2 Divisions of 1Medicinal Chemistry & Pharmacognosy and 2Pharmaceutics & Pharmaceutical Chemistry, College of Pharmacy; 3Division of Medical Oncology, Department of Internal Medicine, College of Medicine; 4Center for Biostatistics, OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH; 5Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan; 6Department of Cancer Biology and Genetics, OSU Comprehensive Cancer Center.
First place (tie) – Hardik Mody
MICRORNA 202-5P DIMINISHES TGFΒ RECEPTOR EXPRESSIONS AND ATTENUATES TGFΒ1-INDUCED EMT IN PANCREATIC CANCER
Hardik R. Mody2, 4, Sau Wai Hung4, Rakesh Pathak2, Jazmine Griffin4, Zobeida Cruz-Monserrate1,3, and Rajgopal Govindarajan1, 2, 4 The 1Comprehensive Cancer Center, 2Division of Pharmaceutics and Pharmaceutical Chemistry, and 3Department of Internal Medicine / Division of Gastroenterology, Hepatology and Nutrition at The Ohio State University; 4Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia