The College of Pharmacy is home to world-renowned researchers who are leading in their fields of study.
Blake R. Peterson, PhD
Dr. Peterson’s research group is working to discover small molecules that affect the proliferation of cancer cells and associated immune cells that support malignancy. To find these compounds, the Peterson laboratory creates fluorescent molecular probes that are designed to facilitate drug discovery. These probes are used in conjunction with phenotypic drug discovery methods to identify both anticancer agents with novel mechanisms of action and their molecular targets. To optimize and evaluate these compounds, they use synthetic organic chemistry, medicinal chemistry, and chemical biology approaches. These strategies, in conjunction with assays based on confocal microscopy, flow cytometry, and other fluorescence-based techniques, provide a platform for the identification of new therapeutic agents.
Dr. Carnes’ research is focused on furthering our understanding of abnormal heart rhythms (arrhythmias) with the goal of optimizing treatment. A particular focus of her program is understanding the underpinnings of arrhythmias occurring during heart failure. A second aspect of Dr. Carnes’ arrhythmia research program is developing and validating processes to improve clinical pharmacy services for patients on long-term antiarrhythmic medication therapy.
Dr. Carnes is also interested in junior faculty development with an emphasis on providing foundations for research independence in clinical and translational research. This work is supported in her role as director of the KL2 scholars program at the Ohio State Center for Clinical and Translational Science.