Dissertation Topics of PhD Graduates


Dissertation Topics of PhD Graduates

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Diego F. Alzate Correa – 2017 (Advisor: K. Hoyt) “Regulation of Suprachiasmatic Nucleus and Hippocampal Cellular Activity as a Function of Circadian Signaling”

Jiexin Cao - 2016 (Advisor: S. Mangel)  "The Circadian Rhythm of Gap Junctions Between Photoreceptors in Goldfish Retina"

Chris Pan - 2016 (Advisor: N. Lee)  "Novel Signaling Mechanisms for Endoglin During Angiogenesi"

Katie Rooney - 2015 (Advisor: L. Wallace)  "A Computational Analysis of Dopamine Signaling at the Level of the Varicosity in Rodent Striatum" - Postdoctoral Researcher running the GenRx Laboratory at COSI in Columbus, Ohio.

Chen Kang - 2015 (Advisor: K. Hu)  "Ion channels, Protein Kinase C and caveolae in cardioprotection" - Postdoctoral Researcher, College of Pharmacy.

Ingrid Bonilla – 2014 (Advisor: C. Carnes) “Acquired Electrophysiological Remodeling and Cardiac Arrhythmias” - Postdoctoral Research Fellow, Dorothy M. Davis Heart and Lung Research Institute, Ohio State University.

Bitna Yi – 2013 (Advisor: D. McKay) "Allosteric Approaches to the Targeting of Neuronal Nicotinic Receptor for Drug Discovery" – Postdoctoral Research Fellow, Stanford University.

Zhaogang Yang – 2012 (Advisor: K. Hu) “Adenosine Receptor-mediated Protein Kinase C Signaling in the Heart” – Postdoctoral Researcher, Mayo Clinic, Rochester, MN.

Brandon Henderson – 2011 (Advisor: D. McKay) "Discovery and Characterization of Selective Negative Allosteric Modulaters of Human 4 2 Neuronal Nicotinic Receptors" – Postdoctoral Research Scholar, California Institute of Technology.

Ryan A. Schneider – 2010 (Advisor: D. Hoyt) ­ “Regulation of Tumor Growth by Synthetic Disintegrins or depletion of PIN1” - Assistant Professor, College of Pharmacy, University of Findlay, Findlay OH

Rachel L. Stevens – 2010 (Advisor: D. Hoyt) ­ “Characterization of Novel Extracellular and Intracellular Modifiers of Apurinic/Apyrimidinic Endonuclease-1” - Assistant Professor, Biology, Freed-Hardeman University, Henderson, TN

Tongzheng Liu - 2009 (Advisor: D. Hoyt, Co-advisor: L. Keshvara) – “Regulation of Endothelial Inflammatory Activation by PIN1” – Postdoctoral Researcher, Mayo Clinic, Rochester, MN.
Vivek  Garg - 2009 (Advisor: K. Hu) – “Regulation of ATP-Sensitive Postassium Channels in the Heart” – Postdoctoral Fellow, The Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah.

Vaibhav B. Shah - 2008 (Advisor: L. Keshvara) – “Molecular and Functional Analysis of Beta-Glucan-Mediated Microglial Activation” - Postdoctoral Researcher, Vanderbilt University Medical Center, Nashville, TN.

Tatiana Gonzalez-Cestari - 2008 (Central University of Venezuela – Advisor: D. McKay) – “Structure-Activity Relationship Studies on the Effects of Analogs of Methyllycaconitine on Neuronal Nicotinic Acetylcholine Receptors”

Raeann Carrier - 2008 (Advisor: K.R. Hoyt) – “Excitotoxicity and Bioenergetics in Huntington’s disease Transgenic Neurons” – Assistant Professor, Lake Erie College of Osteopathic Medicine, Erie, PA.

Tulaya Potaros - 2008 (Advisor: Dr. McKay through Mahidol University, Bangkok) "Intracellular Trafficking of Neuronal Nicotinic Acetylcholine Receptors: Role of the Tumor Supressor Protein, Adenomatous Polyposis Coli"

Bing Han - 2008 (Advisor: J.A. Bauer) – “Mechanistic Consequences of Cardiac Oxidative Stress” - Postdoctoral Researcher, Center for Cardiovascular and Pulmonary Research, Research Institute at Nationwide Children's Hospital, Columbus, OH.

Thong Ma - 2007 (Advisor: Dr. Kari Hoyt) - "The Molecular Mechanisms of Free 3-Nitrotyrosine Neurotoxicity" - Postdoctoral Researcher, Burke Medical Research Institute, White Plains, NY.

Yongcheng Huang - 2007 - (Advisor: Dr. Lakhu Keshvara) - "Structural Functional Analysis of Disabled-1 in Regulation of Reelin Signaling" - Postdoctoral Researcher, University of Texas Southwestern Medical Center, Dallas, TX.

Mandar Joshi - 2005 (Advisor: Dr John Bauer)- "Mechanisms of Nitric Oxide Control in Endothelial and Cardiac Dysfunction"  - Research Fellow, Monash Institute of Medical Research, Melbourne, Australia.

Shawn Pierson-2005 (Advisor: Dr. Anthony Young)- "PACAP38 up-regulates nitric oxide synthase 1 expression via multiple signalling pathways"

Jane Rose-2005 (Advisor Dr. Dale Hoyt)- "Integrin-mediated alterations in chromatin and DNA repair proteins"  - Toxicologist, Central Product Safety, Procter & Gamble, Cincinnati, OH.

Reshma Baliga-2004 (Advisor: Dr. John Bauer)- "Roles and mechanisms of oxidant stress in cardiovascular disease" – Research Scientist, University College London, London, UK.

Hong Huang-2004 (Advisor: Dr. Dale Hoyt)- "Inflammatory and oxidative mechanisms in endothelial cell activation and dysfunction" – Research Scientist, Center for Cardiovascular and Pulmonary Research, Research Institute at Nationwide Children's Hospital, Columbus, OH.

Alysia Chaves-2003 (Advisor: Dr. Bauer)- "Mechanisms of AIDS and cocaine related cardiovascular disease" – Merck Research Laboratories, West Point, PA.

Deepali Pitre-2003 (Advisor: Dr. Bauer)- "Oxidative Mechanisms in Diabetes Related Urinary Bladder Dysfunction.”

Bryan Wenger-2003 (advisor: Dr. McKay)-"Expression of Multiple Populations of Nicotinic Acetylcholine Receptors in Bovine Adrenal Chromaffin Cells"

R. Benjamin Free-2002 (Advisor: Dr. McKay)- "Characterization and Regulation of Adrenal Neuronal Nicotinic Acetylcholine Receptors"  - Research Scientist, National Institutes of Health, Bethesda, MD.

Michael Mihm-2000 (Advisor: Dr. Bauer)- "Mechanistic Aspects of Cardiovascular Peroxynitrite Formation" – Eli Lilly and Company, Indianapolis, IN.

Suvara K. Wattanapitayakul - 2000 (Advisor: Dr. Bauer) - "Roles and Mechanisms of Oxidative Pathways in Cardiovascular Disease" – Assistant Professor, Department of Pharmacology, Srinakharinwirot University, Bangkok, Thailand.

John Battisti - 1999 (Co-Advisors: Dr. Uretsky and Dr. Wallace) - "The Role of Drug-Associated Cues in Behavioral Sensitization Induced by Psychostimulant Drugs"

Scott Hayes - 1997 (Advisor: Dr. Young) - "Novel Aspects of Glucocorticoid Hormone Action in the Chicken Retina"

Longping Lei - 1997 (Advisor: Dr. Feller) - "Pharmacological Characterization of the Calcium Channel Mediated Properties of 2-(4-Isothiocyanatobenzyl) Imidazoline Analogs in Smooth and Skeletal Muscles"

Jane Li - 1997 (Advisor: Dr. Young) - "Glial Cell selective Expression of the Glutamine Synthetase Gene"

Ratnavali Mehta - 1997 (Advisor: Dr. Feller) - "Pharmacological Evaluation of Trimetoquinol Analogs as Affinity Ligands for -Adrenergic Receptor Systems"

Shamina Rangwala - 1997 (Advisor: Dr. Feller) - "In Vitro Mechanistic Studies of Peroxisome Proliferation by Chiral Chlofibrate Analogs"

David Weinstein - 1997 (Advisor - Dr. Wallace) - "Structure Activity and Molecular Modeling Studies of the AMPA Receptor: Towards a Conceptual Understanding of the Ligand Binding Site"

Marina Bergman - 1996 (Advisor: Dr. Holycross) - "Pharmacological Modulation of Myocardial TumorNecrosis Factor -Secretion by Phosphodiesterase Inhibitors in Heart Failure Prone Rats"

Jay Byrnes - 1996 (Advisor: Dr. Wallace) - "Cyclic AMP Mechanisms in the Ventral Tegmental Area: Mediation of the Behavioral Effects of Amphetamine"

Cynthia Carnes - 1996 (Advisor: Dr. Wallace) - "Effects of Thiopental, Ketamine, and Propofol on the Inward Rectifier Potassium Current in Rat Ventricular Myocytes"

Anish Konkar - 1996 (Advisor: Dr. Feller) - "Pharmacological Evaluation of the -Adrenoceptor Subtype Interactions of Trimetoquinol (TMQ) and Related Analogs"

Shridhar Naraynan - 1996 (Advisor: Dr. Uretsky) - "Effect of Pertussis Toxin Injected into the Ventral Tegmental Area on Postsynaptic Mechanisms in the Nucleus Accumbens:Implications for a Model of Psychostimulant Sensitization"

Jinling Xie - 1996 (Advisor : Dr. Young) - "Transcriptional Control via Multiple Promoters in the CNS: Glial Filamin and Neuronal Nitric Oxide Synthase Gene Expression"

David Beard - 1995 (Advisor: Dr. Young) - "Cell-selective Expression of a Glutamine Synthetase Fusion Gene in Embryonic Chick Retina"

Jennifer Maurer - 1994 (Advisor: Dr. McKay) - "Effects of Protein Kinase Inhibitors on Cultured Adrenal Chromaffin Cells: Evidence for the Role of Protein Phosphorylation Reactions in Calcium Homeostasis

Paul Fraundorfer - 1993 (Advisor: Dr. Feller) - "Functional and Biochemical Characterization of Trimetoquinol (TMQ) Analog Interactions with ß-Receptor Subtypes"

Tahira Faroouqi - 1992 (Advisor: Dr. Uretsky) - "Interaction of Permanently Charged Dopaminergic Agonists and Antagonists with D2 Dopamine Receptors"

Hyangja Gu - 1992 (Advisor: Dr. McKay) - "The Effects of Antimitotic Drugs and mAb35 on -Tubulin mRNA, Microtubules and Nicotinic Receptor-Mediated Catecholamine Secretion in Adrenal Chromaffin Cells in Culture"

Farida G. Kaddis - 1992 (Advisor: Dr. Uretsky) - "Role of AMPA/Kainate Receptors in the Nucleus Accumbens in Mediating Locomotor Stimulatory and Rewarding Effects of Cocaine"

Rick Layer - 1992 (Advisor: Dr. Wallace) - "Modulation of Hyperactivity and Reward by Excitatory Amino Acid, Serotonin, and Opiate Receptors in Nucleus Accumbens"

Isabel Lopez - 1992 (Advisor: Dr. McKay) - "Effects of Antimitotic Agents on Cultured Adrenal Chromaffin Cells: Implications for Microtubule Involvement with Adrenal Nicotinic Receptors"

David Willins - 1992 (Advisor: Dr. Uretsky) - "The Role of Excitatory Amino Acid Receptors in the Basal Forebrain in the Locomotor Response Produced by Psychostimulants and the Non-Competitive NMDA Receptor Antagonist MK801"

Catherine Barry - 1991 (Advisor: Dr. Young) - "The Cloning and Primary Structure of Glial Filamin"

Tim Esbenshade - 1991 (Advisor: Dr. Feller) - "Pharmacological Characterization of 1-AdrenergicReceptor Mediated DNA and Protein Syntheses in Primary Cultured Rat Hepatocytes"

Urusa Intrasuksri - 1991 (Advisor: Dr. Feller) - "The Role of Fatty Acids and Related Analogs in Mediating Peroxisome Proliferation in Primary Cultures of Rat Hepatocytes"

Yangmee Shin - 1991 (Advisor: Dr. Feller) - "Pharmacological Characterization of Thromboxane A2/Prostaglandin H2 Receptors in Platelets, Vascular Endothelial and Vascular Smooth Muscle Cells Using Trimetoquinol Analogs"

Donna Supko - 1991 (Advisor: Dr. Wallace) - "The Role of Glutamate Receptors in the Zona Incerta in Mediating the Effects of Amphetamine"

Bob Boldry - 1990 ( Advisor: Dr. Uretsky) - "Role of Dopaminergic Neurotransmission in Hypermotility Response Produced by Intra-Accumbens Administration of AMPA"

Haifeng Pu - 1990 (Advisor: Dr. Young) - "Expression of a Cloned Chicken Glutamine Synthetase Gene in Transfected Retina"

Wai-Shiu Wong - 1990 (Advisor: Dr. Rahwan) - "The Antiulcer Activity of the Calcium Antagonist Propyl-Methylenedioxindene"

Paul Shreve - 1989 (Advisor: Dr. Uretsky) - "The Role of Excitatory Amino Acids in the Nucleus Accumbens and Subpallidal Region in Goal Directed Locomotor Activity"

Gerald Patejunas - 1989 (Advisor: Dr. Young) - "Regulation of Chicken Retinal Glutamine Synthetase During Development"

Tom Kocarek - 1988 (Advisor: Dr. Feller) - "Effects of Hypotriglyceridemic Drugs on Peroxisome Proliferation-Associated Enzyme Activities and Glycerolipid Biosynthesis in Primary Cultures of Rat Hepatocytes"

Elizabeth Kudlacz - 1988 (Advisor: Dr. Wallace) - "Effects of Diabetes and Diuresis on In Vivo and In Vitro Function of Rat Urinary Bladder"

Mark Olah - 1988 (Advisor: Dr. Rahwan) - "Effects of Calcium Channel Blockade and Intracellular Calcium Antagonism on Endothelium-Dependent Responses of Isolated Rat Aorta and Influence of Endothelium on Drug Action"

Xiao-ying Tien - 1988 (Advisor: Dr. Wallace) - "Effects of Kinins on Electrolyte Transport Across Normal and Inflamed Rat Distal Colon in Vitro"

Alexa Chun - 1987 (Advisor: Dr. Wallace) - "The Effects of Age on Urinary Bladder Function in the Male Rat: Response to Pharmacological Agents"

Raye Ann Wallace - 1987 (Advisor: Dr. Uretsky) - "The Interaction of Structural Analogs of Dopamine, Chlorpromazine and Sulpiride with Striatal Dopamine Receptors"

Philip Ross - 1986 (Advisor: Dr. Burkman) - "Studies on the Adrenergic and Dopaminergic Activities of Sulfur-Containing Catecholamine Analogs"

Robert Stephens - 1986 (Advisor: Dr. Uretsky) - "Characterization of a Folate-Induced Hypermotility Response after Bilateral Injection into the Rat Nucleus Accumbens"