Ema Cocucci

Ema Cocucci

Ema Cocucci, MD, PhD

Assistant Professor
Unit / Department / Division
Pharmaceutics and Pharmacology
412 Biomedical Research Tower
Email Address
Phone Number

Professional Interests

Professional Interests

Dr. Cocucci studies basic mechanism of membrane trafficking and is interested in how these processes deviate during cancer development when compared to normal cells. His research adopts multiple techniques, including traditional biochemistry, cell biology, and high resolution fluorescent live cell microscopy. Dr. Cocucci’s goal is to define novel targets for cancer therapy and to improve drug delivery, studying the internalization pathways and the mechanisms of endosomal escape adopted by artificial and biological nanovectors.


  • 2008, PhD - Molecular Medicine, Vita-Salute San Raffaele University
  • 2004, Board in Pharmacology - Clinical Pharmacology, Universita degli Studi di Milano
  • 2000, MD - Medicine and Surgery, Universita degli Studi di Milano


  • Advanced Imaging Center (AIC), 2017
  • GlaxoSmithKline and Immune Disease Institute Fellowship, 2008 - 2010
  • FEBS Short Term Fellowship, 2006
  • Marie Curie Fellowship, 2002 - 2003

Journal Articles

  • Aguet F, Cocucci E. Measuring Clathrin-Coated Vesicle Formation with Single-Molecule Resolution. Methods Mol Biol. 2018;1847:197-216.
  • Minciacchi VR, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, Li X, Mishra R, Chiarugi P, Adam RM, Posadas EM, Viglietto G, Freeman MR, Cocucci E, Bhowmick NA, Di Vizio D. MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer. Cancer Res. 2017 05 01;77(9):2306-2317.
  • Cocucci E, Kim JY, Bai Y, Pabla N. Role of Passive Diffusion, Transporters, and Membrane Trafficking-Mediated Processes in Cellular Drug Transport. Clin Pharmacol Ther. 2017 Jan;101(1):121-129.
  • Ter-Ovanesyan D, Kowal EJK, Regev A, Church GM, Cocucci E. Imaging of Isolated Extracellular Vesicles Using Fluorescence Microscopy. Methods Mol Biol. 2017;1660:233-241.