Craig A. McElroy

Craig McElroy

Craig A. McElroy, PhD

Research Assistant Professor
Unit / Department / Division
Medicinal Chemistry and Pharmacognosy
Email Address
Phone Number

Journal Articles

  • Yoder, R.J.; Zhuang, Q.; Beck, J.M.; Franjesevic, A. et al. Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase. ACS Med Chem Lett. 2017 Jun; 8(6):622-627.
  • Wang, J.; Li, B.; Zhao, W.; Zhang, X. et al. Two-Photon Near Infrared Fluorescent Turn-On Probe Toward Cysteine and Its Imaging Applications ACS SENSORS. 2016 Jul; 1(7):882-887.
  • Zhuang, Q.; Young, A.; Callam, C.S.; McElroy, C.A. et al. Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase. Ann N Y Acad Sci. 2016 Jun; 1374(1):94-104.
  • Chapleau, R.R.; McElroy, C.A.; Ruark, C.D.; Fleming, E.J. et al. High-Throughput Screening for Positive Allosteric Modulators Identified Potential Therapeutics against Acetylcholinesterase Inhibition. J Biomol Screen. 2015 Oct; 20(9):1142-1149.
  • Ihms, E.C.; Zhou, M.; Zhang, Y.; Kleckner, I.R. et al. Gene regulation by substoichiometric heterocomplex formation of undecameric TRAP and trimeric anti-TRAP. Proc Natl Acad Sci U S A. 2014 Mar; 111(9):3442-3447.
  • Kleckner, I.R.; McElroy, C.A.; Kuzmic, P.; Gollnick, P. et al. Homotropic cooperativity from the activation pathway of the allosteric ligand-responsive regulatory trp RNA-binding attenuation protein. Biochemistry. 2013 Dec; 52(49):8855-8865.
  • Agarwal, H.K.; McElroy, C.A.; Sjuvarsson, E.; Eriksson, S. et al. Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1. Eur J Med Chem. 2013 Feb; 60 456-468.
  • McElroy, C.A.; Holland, P.J.; Zhao, P.; Lim, J-M. et al. Structural reorganization of the interleukin-7 signaling complex. Proc Natl Acad Sci U S A. 2012 Feb; 109(7):2503-2508.
  • Sachleben, J.R.; McElroy, C.A.; Gollnick, P.; Foster, M.P. Mechanism for pH-dependent gene regulation by amino-terminus-mediated homooligomerization of Bacillus subtilis anti-trp RNA-binding attenuation protein. Proc Natl Acad Sci U S A. 2010 Aug; 107(35):15385-15390.
  • Amero, C.D.; Byerly, D.W.; McElroy, C.A.; Simmons, A. et al. Ligand-induced changes in the structure and dynamics of Escherichia coli peptide deformylase. Biochemistry. 2009 Aug; 48(32):7595-7607.
  • McElroy, C.A.; Dohm, J.A.; Walsh, S.T.R. Structural and biophysical studies of the human IL-7/IL-7Ralpha complex. Structure. 2009 Jan; 17(1):54-65.
  • Foster, M.P.; McElroy, C.A.; Amero, C.D. Solution NMR of large molecules and assemblies. Biochemistry. 2007 Jan; 46(2):331-340.
  • McElroy, C.A.; Manfredo, A.; Gollnick, P.; Foster, M.P. Thermodynamics of tryptophan-mediated activation of the trp RNA-binding attenuation protein. Biochemistry. 2006 Jun; 45(25):7844-7853.
  • Boomershine, W.P.; McElroy, C.A.; Tsai, H-Y.; Wilson, R.C. et al. Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P. Proc Natl Acad Sci U S A. 2003 Dec; 100(26):15398-15403.
  • McElroy, C.; Manfredo, A.; Wendt, A.; Gollnick, P. et al. TROSY-NMR studies of the 91kDa TRAP protein reveal allosteric control of a gene regulatory protein by ligand-altered flexibility. J Mol Biol. 2002 Oct; 323(3):463-473.
  • Byerly, D.W.; McElroy, C.A.; Foster, M.P. Mapping the surface of Escherichia coli peptide deformylase by NMR with organic solvents. Protein Sci. 2002 Jul; 11(7):1850-1853.