Distinguished Lecture to Feature Cardiovascular and Renal Research Pioneer

04/11/2016

The Ohio State University College of Pharmacy is pleased to present University of Pittsburgh Department of Pharmacology and Chemical Biology’s Edwin Jackson, PhD on Tuesday, April 12, 4:00 p.m., Room 111, Lloyd M. Parks Hall, 500 West 12th Ave. Jackson’s talk, “Discovery of a New Class of Non-Canonical Nucleotides: From the Kidney and Back Again,” is part of the 2016 Distinguished Lecture series.

Edwin Jackson, Ph.D. is professor of Pharmacology and Chemical Biology and of Medicine at the University of Pittsburgh. He has 40 years of experience in the area of cardiovascular and renal research, and has been working in the area of adenosine/purine research for 36 years. He has investigated the roles of adenosine as a regulator of the renin-angiotensin system; renal hemodynamics; renal tubular function; growth of cardiovascular/renal cells (including cardiac fibroblasts, vascular smooth muscle cells, glomerular mesangial cells and renal epithelial cells); and renal sympathetic neurotransmission. He also has investigated the role of adenosine as a regulator of the immune system and inflammation and in the pathophysiology of cancer, as well as the use of adenosine for treating myocardial infarction.

Jackson has 14 issued patents, many of which relate to adenosine pharmacology. He has continually developed novel methods for quantifying purines, culminating in his latest deployment of LC-MS/MS. Using these methods, he has discovered that kidney alkaline phosphatase importantly contributes to renal adenosine production.  

Jackson received a BS in Pharmacy from the University of Texas at Austin and a PhD in Pharmacology from University of Texas Southwestern Medical Center. He was a postdoctoral fellow in Clinical Pharmacology at Vanderbilt University. He has held a number of professional positions, most notably at University of Texas at Austin, Vanderbilt and the University of Pittsburgh. He currently runs an active NIH-funded research laboratory, which investigates the biochemistry, molecular/cell biology, and physiology/pharmacology of adenosine.